A xenobiotics-inactivating hemoprotein related to the class of pharmacologically active compounds (cholinolytics) was detected in rat blood. Ammonium sulphate fractionation, DEAE cellulose chromatography and gel filtration on Sephadex G-75 resulted in 750-fold purification of the protein; its Mr = 73 000-80 000. Multiple injections of the protein to experimental animals led to a 2-3-fold increase of the protein content in the blood.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
[blood protein-inactivating
4
protein-inactivating atropine]
4
atropine] xenobiotics-inactivating
4
xenobiotics-inactivating hemoprotein
4
hemoprotein class
4
class pharmacologically
4
pharmacologically active
4
active compounds
4
compounds cholinolytics
4
cholinolytics detected
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!