Unlabelled: A collateral effect of the COVID-19 pandemic has been the discontinuity of treatments, a highly sensitive situation for chronic patients.
Aim: to describe the factors associated with discontinuing treatments in chronic patients over 18 years old residing in Chile during the COVID-19 pandemic.
Methods: A secondary analysis of the database of the MOVID-IMPACT-C survey, which corresponds to a cross-sectional study with national urban representativeness, was carried out in 2020. Social and health factors were defined as explanatory variables, and treatment discontinuity as a response variable. The proportion of chronic patients who discontinued their treatment, crude and adjusted OR, was estimated using multivariate logistic regression models.
Results: 40.42% of chronic patients discontinued their treatments. Those whose last consultation was at the "tertiary" level (OR= 0.58) or at the "emergency" level (OR= 0.14) were less likely to have discontinued treatment than those who attended at the "primary" level, independently of the provider (public/private). Chronic patients whose pre-existing health was diabetes were more likely to have discontinued treatment (OR= 1.57). In addition, a strong association was observed between those who discontinued their treatments and perceived worsening of their health status (OR= 2.25).
Conclusions: A high discontinuity of treatment was observed during the COVID-19 pandemic in chronic patients in Chile, with hypertensive patients being the most affected and patients with diabetes the most likely to be disrupted. It was observed that patients under control due to major cardiovascular events were the ones who discontinued their treatments the least, which may be indicative of a good response from the system in prioritizing patients with greater severity or emergency. There is a relevant worsening of the self-perceived health of chronic patients who discontinued their treatments.
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http://dx.doi.org/10.4067/s0034-98872024001001038 | DOI Listing |
Ann Med
December 2025
Department of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Background: Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous condition with different risk factors, including family history. This study aimed to explore association between a family history of chronic airway disease and features and outcomes of COPD.
Methods: Participants were obtained from the RealDTC study between December 2016 and December 2022.
An Bras Dermatol
March 2025
Department of Dermatology, Faculty of Medicine, Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address:
Background: Chronic pruritus is the defining symptom of atopic dermatitis (AD). Although AD is common in Latin America, there is little data regarding pruritus intensity, characteristics, and effects on quality of life in this population.
Objective: This cross-sectional study aimed to evaluate pruritus in 91 patients with AD at a tertiary university hospital in São Paulo, Brazil.
J Microbiol Immunol Infect
March 2025
Division of Pediatric Infectious Diseases, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; Chang Gung University School of Medicine, Taoyuan, Taiwan. Electronic address:
Background: Strict mask wearing and handwashing were implemented in hospital settings during COVID-19 pandemic in Taiwan. To explore if nasal methicillin-resistant Staphylococcus aureus (MRSA) carriage rate among inpatients in the hospital changed before and after COVID-19, we conducted this study.
Methods: Patients who were admitted to a regional hospital in central Taiwan during one week in 2012 and 2023, respectively, were enrolled.
ESC Heart Fail
March 2025
Institute of Health Informatics Research, University College London, London, UK.
Aims: Atrial fibrillation (AF) is a frequent comorbidity in heart failure (HF). We analysed factors associated with new-onset atrial fibrillation in patients with heart failure using linked real-world UK data from primary and secondary care, along with findings from genome-wide association studies.
Methods And Results: Among 163 174 participants with a diagnosis of HF (January 1998 to May 2016) from Clinical Practice Research Datalink (CPRD) and Hospital Episodes Statistics (HES), 111 595 participants had no previous history of AF (mean age 76.
JACC Cardiovasc Interv
March 2025
Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University of Duisburg-Essen, Essen, Germany.
A global treatment algorithm was developed for the endovascular revascularization of femoropopliteal lesions and chronic total occlusions, aiming toward a more standardized approach to endovascular treatment in patients with peripheral artery disease. The following steps are proposed. 1) Evaluation of lesion morphology based on preprocedural imaging by Duplex sonography and intravenous ultrasound for selection of lesion preparation tools.
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