Following the publication of the above paper, a concerned reader drew to the Editor's attention that certain discrete western blot data shown in the RT‑qPCR blots in Figs. 1A and 2A, and western blot data in Fig. 5 were strikingly similar to data that had already appeared in previously published papers in different journals written by different authors at different research institutes. Furthermore, some of the protein bands featured in the western blots in Figs. 1C, 2C and 4 were strikingly similar to other bands within the same figures, suggesting that the figures in question may have undergone inappropriate editing. Having considered the issues identified, the Editor of has decided that this article should be retracted from the Journal on account of the re‑use of previously published data and the uncertainties regarding the presentation of data in Figs. 1C, 2C and 4. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused. [Oncology Reports 30: 3032‑3038, 2013; DOI: 10.3892/or.2013.2785].
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http://dx.doi.org/10.3892/or.2025.8882 | DOI Listing |
Aging Dis
February 2025
Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
Studies have linked inhalation anesthesia and surgery to increased cognitive impairment, particularly in the elderly. Our previous research showed that isoflurane, but not desflurane, affected cognitive function in mice by modulating cyclophilin D (CypD), a key regulator of the mitochondrial permeability transition pore (mPTP) and mitochondrial function. Both anesthetics metabolize into trifluoroacetic acid (TFA), which is associated with cognitive deficits.
View Article and Find Full Text PDFJ Agric Food Chem
March 2025
College of Food Science and Technology, National Center of Meat Quality and Safety Control, Nanjing Agricultural University, Nanjing 210095, China.
Costameres are essential for maintaining the integrity of muscle fibers, which affects the meat tenderness. To explore the pattern of alteration in costameres after slaughter, this study investigated the distribution of costamere proteins (desmin, talin-2, vinculin, and integrin β1), their impact on tenderness, and the involved enzymes. Western blot analysis showed that talin-2 significantly degraded in postmortem, while integrin β1 significantly increased at 48 h ( < 0.
View Article and Find Full Text PDFEndokrynol Pol
March 2025
Department of Metabolic Endocrinology, Zhuzhou Central Hospital, Zhuzhou, China.
Introduction: The proprotein convertase subtilisin/kexin type 9/lectin-like oxidized low-density lipoprotein receptor-1 (PCSK9/LOX-1) axis plays a crucial role in regulating vascular endothelial cell function, but its specific involvement in type 2 diabetes mellitus (T2DM) remains unclear. This study aims to explore the potential mechanism of the PCSK9/LOX-1 axis in high-glucose (HG)-induced vascular endothelial cell dysfunction.
Material And Methods: Peripheral blood samples were collected from T2DM patients to analyse the correlation between PCSK9 and blood lipid levels.
Endokrynol Pol
March 2025
Department of Clinical Laboratory, the First Affiliated Hospital of Guangxi Medical University, Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, Nanning, Guangxi, China.
Introduction: Thiamine-responsive megaloblastic anaemia syndrome (TRMA) is a rare genetic disease caused by mutations in the SLC19A2 gene that encodes thiamine transporter 1 (THTR-1). The common manifestations are diabetes, anaemia, and deafness. The pathogenic mechanism has not yet been clarified.
View Article and Find Full Text PDFEndokrynol Pol
March 2025
Medical Genetics Department and Prenatal Diagnosis Centre, The Affiliated Hospital of Qingdao University, Qingdao, China.
Background: Congenital hypothyroidism (CH) is the most common neonatal disorder, primarily caused by thyroid dysgenesis (TD). While the genetic cause has been identified in less than 5% of TD cases, there is an urgent need to investigate additional gene mutations that may be responsible. In 2018, TUBB1 was identified as a novel candidate gene associated with TD.
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