HLA-B*18:01:56 showed two synonymous nucleotide differences compared to the HLA-B*18:01:01:01 allele in codons 224 and 225.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/tan.70098 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Variations and Hematological Adaptations to High-Altitude Hypoxia in Indigenous Goats in Yunnan Province, China.
Animals (Basel)
February 2025
Faculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
The gene plays a central role in hypoxia adaptation in high-altitude animals. Using over 400 blood samples from goats across elevations in Yunnan (500-3500 m), this study examined hematological traits, genetic polymorphisms, and protein structure. Red blood cell (RBC) and hemoglobin (HGB) levels increased significantly with altitude ( < 0.
View Article and Find Full Text PDFAnalysis of synonymous codon usage bias in the chloroplast genome of five Caragana.
BMC Plant Biol
March 2025
College of Eco-Environmental Engineering, Qinghai University, Xining, 810016, China.
Background: The genus Caragana, known for its adaptability and high forage value, is commonly planted to rehabilitate barren land and prevent desertification. Several Caragana species are also used for medicinal purposes. Analysis of synonymous codon usage bias and their primary influencing factors in chloroplast genomes aims to provide insights into molecular research and germplasm innovation for Caragana plants.
View Article and Find Full Text PDFIdentification of candidate genes associated with resistance to aflatoxin production in peanut through genetic mapping and transcriptome analysis.
Theor Appl Genet
March 2025
Key Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture and Rural Affairs, Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, Wuhan, China.
Two major QTLs qAftA07and qAftB06.2 for peanut aflatoxin production resistance were identified and candidate genes for them were predicted. Peanut (Arachis hypogaea L.
View Article and Find Full Text PDFComputational and molecular insights on non-synonymous SNPs associated with human RAAS genes: Consequences for Hypertension vulnerability.
J Genet Eng Biotechnol
March 2025
Department of Bioinformatics, Pharmacogenomics and CADD Lab, Alagappa University, Karaikudi, Tamil Nadu, India. Electronic address:
Hypertension is the foremost modifiable risk factor for cardiovascular and renal diseases, and overall mortality on a global scale. Genetic variants have the potential to alter an individual's drug responses. In the present study, we employed a comprehensive computational analysis to evaluate the structural and functional implications of deleterious missense variants to examine the influence of RAAS genes such as AT1R, AT2R, and MasR on susceptibility to hypertension.
View Article and Find Full Text PDFBeyond pills and prescriptions: Exploring aging-related diseases with non-pharmacological strategies and molecular innovations.
Aging Dis
February 2025
International Center for Neuroscience Research, Institute for Intelligent Research, Tbilisi, Georgia.
This paper provides a thorough examination of aging-related diseases, exploring into the intricate molecular mechanisms that underline their development and progression. It explores cutting-edge therapeutic interventions aimed at addressing these conditions, with a particular focus on non-pharmacological approaches such as personalized lifestyle modifications, cognitive enhancement strategies, and robust social engagement initiatives. Additionally, it highlights emerging modalities including gene therapy and precision medicine as promising avenues for mitigating the challenges associated with age-related ailments.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!