Objectives: Treatment outcomes for patients with arrhythmias, deep vein thrombosis, prosthetic valves, blood thinning, and cardiac issues/chest pain problems can be affected by knowledge about oral anticoagulant therapy. The primary objective is to assess the knowledge of patients using oral anticoagulants for anticoagulation therapy, and the secondary aim is to identify factors influencing the level of anticoagulation knowledge.
Materials And Methods: This prospective cross-sectional study was conducted at selected community pharmacies. A 33-item, self-administered questionnaire was adopted to evaluate patient understanding of anticoagulant medication in the urban population. Scores were calculated for each part and the association between patients' knowledge. Binary logistic regression analysis was performed to assess variables associated with oral anticoagulation knowledge among participants.
Results: The mean percentage knowledge score of the study population (n=323) was 42.38±12.5. Age has been found to have a negative correlation with anticoagulant therapy knowledge (=0.01). It was discovered that there were gaps in knowledge regarding critical areas of use and self-management, including the identification of bleeding as a serious side effect of medication, drug-drug interactions, and dose omission.
Conclusion: This research article highlights urban participants' knowledge gaps in oral anticoagulation. Targeted educational interventions by pharmacists are vital for improving patient safety and treatment outcomes. Advancing age was associated with knowledge. Further research could explore the long-term impacts of educational interventions in larger populations.
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http://dx.doi.org/10.4274/tjps.galenos.2024.80069 | DOI Listing |
Cells
February 2025
Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy.
The thrombotic physiopathology of antiphospholipid syndrome (APS) is complex, heterogeneous, and dynamic. While venous thromboembolism (VTE) is the most common initial presentation, arterial thrombotic events (ATE) become more frequent in advanced stages and are associated with high morbidity and mortality. Despite the use of oral anticoagulants (OACs), thrombotic APS remains associated with a high risk of recurrent thrombosis.
View Article and Find Full Text PDFAm J Emerg Med
February 2025
Department of Emergency Medicine, Good Samaritan University Hospital, West Islip, NY, United States. Electronic address:
Introduction: Data on the utility of coagulation factor testing (INR, aPTT) in non-anticoagulated patients with low-risk trauma is limited. In this study, we describe the rate in which coagulation studies are ordered this population and report the frequency in which these tests were abnormal and resulted in intervention.
Methods: This was a multi-center retrospective observational study evaluating patients aged 65 years and older with low-risk mechanical falls not on chronic oral anticoagulation.
Intern Med J
March 2025
Department of Neurosciences, Eastern Health, Melbourne, Victoria, Australia.
Direct oral anticoagulants (DOACs) are used for stroke prevention in atrial fibrillation, but their presence can limit thrombolysis eligibility in acute stroke. This retrospective study examined whether rapid plasma DOAC testing expanded eligibility for thrombolysis. Among ischaemic stroke patients taking DOACs who were otherwise eligible for thrombolysis, 40% had low DOAC levels (<50 ng/mL).
View Article and Find Full Text PDFRev Esp Enferm Dig
March 2025
Gastroenterology and Endoscopy, Hospital Clínic Barcelona, Spain.
A 71-year-old man presented for a routine physical examination with multiple comorbidities, including severe panvascular disease and valvulopathy, requiring anticoagulation therapy. He had a history of chronic hemolytic anemia and had been taking oral ferrous sulfate for two years. Upper gastrointestinal endoscopy (UGE) was performed, as part of the study of the persist anemia, revealing an extensive nodular area with multiple brownish deposits and spontaneous hemorrhage.
View Article and Find Full Text PDFInt J Cardiol Congenit Heart Dis
March 2025
Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation, London, United Kingdom.
Advances in medical care have significantly extended the lifespan of patients with congenital heart disease (CHD), allowing most to survive into adulthood. However, they continue to face significant cardiovascular morbidity, particularly atrial arrhythmias (AA), heart failure, and thromboembolic (TE) events. TE events in adult CHD patients arise from various factors, including AA, intracardiac repairs, cyanotic CHD, Fontan palliation, pregnancy, and mechanical heart valves (MHV).
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