A recent paper by Xu et al. proposes that cognitive maps in mice emerge during spatial navigation from path integration anchored to a starting position. We challenge this understanding by arguing that enclosure geometry rather than path integration shapes cognitive maps. Our view emphasizes the context-specific formation of cognitive maps, claiming that these maps arise in response to particular task demands rather than existing as fixed, independent entities.
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http://dx.doi.org/10.1111/ejn.70059 | DOI Listing |
Front Neurosci
February 2025
York Neuroimaging Centre, University of York, York, United Kingdom.
Introduction: A full understanding of how we see our world remains a fundamental research question in vision neuroscience. While topographic profiling has allowed us to identify different visual areas, the exact functional characteristics and organization of areas up in the visual hierarchy (beyond V1 & V2) is still debated. It is hypothesized that visual area V4 represents a vital intermediate stage of processing spatial and curvature information preceding object recognition.
View Article and Find Full Text PDFNutrients
February 2025
Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 8AF, UK.
Autism and ADHD shape behaviours related to food, exercise, and body image, potentially influencing obesity treatment outcomes, as seen in eating disorder research. Resultantly, autistic and ADHD patients with obesity may have distinct experiences and differences compared to non-autistic and non-ADHD patients. This review maps existing literature on autism and ADHD in adults with obesity.
View Article and Find Full Text PDFNat Commun
March 2025
State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Stress Biology, School of Agriculture and Biotechnology, The Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Shenzhen, 518107, China.
Comparative genomic studies can identify genes under evolutionary constraint or specialized for trait innovation. Growing evidence suggests that evolutionary constraint also acts on non-coding regulatory sequences, exerting significant impacts on fitness-related traits, although it has yet to be thoroughly explored in plants. Using the assay for transposase-accessible chromatin by sequencing (ATAC-seq), we profile over 80,000 maize accessible chromatin regions (ACRs), revealing that ACRs evolve faster than coding genes, with about one-third being maize-specific and regulating genes associated with speciation.
View Article and Find Full Text PDFNeurosci Biobehav Rev
March 2025
Neuroscience and Mental Health, The Hospital for Sick Children, Canada; Institute of Biomedical Engineering, University of Toronto, Toronto, Canada; Division of Neurosurgery, The Hospital for Sick Children, Canada.
Fragile X syndrome (FXS), caused by FMR1 gene mutations, leads to widespread brain alterations significantly impacting cognition and behaviour. Recent advances have provided a deeper understanding of the neural substrates of FXS. This review provides a comprehensive overview of the current knowledge of neuronal network alterations in FXS.
View Article and Find Full Text PDFEur J Paediatr Neurol
March 2025
School of Psychology, University of East London, London, UK. Electronic address:
Background: Neonatal Hypoxic-Ischaemic Encephalopathy (HIE) increases the risk for neurodevelopmental impairment. Information on school-age memory function is limited in children who received hypothermia treatment (TH) for neonatal HIE.
Objectives: To evaluate memory function in school-aged children who had neonatal HIE and TH and survived without major neuromotor impairment.
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