Background: Anterior cruciate ligament (ACL) tears combined with medial collateral ligament (MCL) injury has been associated with an increased rate of ACL reconstruction (ACLR) failure, high-grade pivot shift (PS), and lower return to sports rate. On the other hand, medial-sided procedures in the setting of ACLR are associated with knee stiffness and arthrofibrosis.
Purpose/hypothesis: This study aimed to compare clinical scores, objective knee laxity, failure, and complication rates in 2 different patient groups. The combination of ACL reconstruction with LET and the Hughston procedure yields comparable failure rates, complication rates, and clinical outcomes to ACL reconstruction with LET in patients without medial instability.
Study Design: Cohort study; Level of evidence, 3.
Methods: A group of patients had a combined ACL and MCL injury grade 2 with chronic instability and underwent ACLR associated with lateral extra-articular tenodesis (LET) and the Hughston procedure (Hughston group). The control group included matched patients with isolated ACL lesion without medial instability who underwent ACL reconstruction with LET (control group). Patient-reported outcome measures, complications, and reoperations were collected for both groups. A clinical evaluation was performed including objective anteroposterior laxity measurement (KT-1000 arthrometer) and PS quantification. The primary outcomes were ACL revision and ACL-clinical failure, a composite parameter of anteroposterior and rotatory laxity. A test for 2-way analysis of variance for repeated measures was performed to assess the between-group differences ( < .05). Surgical and clinical failure were assessed via Kaplan-Meier method.
Results: A total of 70 patients (35 per group) were enrolled in the present study at a follow-up of 8.1 ± 2.7 years. All the patient-reported outcome measures significantly improved at the final follow-up with no difference between the 2 groups ( > .05). ACL revision was performed in 2 of 35 (5.7%) patients in both groups ( = .79). A total of 10 patients (4 in the Hughston group and 6 in the control group) were excluded from the analysis of the clinical failures due to contralateral-side injury. Clinical failure was identified in 7 of 28 (25.0%) patients in the Hughston group and 5 of 29 (17.2%) in the control group ( = .59). Reoperation due to knee stiffness was required only in 1 of 35 patients (2.9%) of the Hughston group.
Conclusion: Due to its simplicity and cost-effectiveness, the Hughston technique should be included in the orthopaedic surgeon's armamentarium for the treatment of moderate anteromedial instability in combined ACL and MCL injury. Moreover, the outcomes and failure rate of the Hughston technique combined with an ACLR + LET are similar to that of an ACLR + LET used to treat an isolated ACL injury.
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http://dx.doi.org/10.1177/23259671241309651 | DOI Listing |
J Pediatr Orthop
March 2025
Orthopédie Traumatologie, Hôpital des Enfants, CHU de Toulouse, Toulouse, France.
Background: Pediatric anterior cruciate ligament reconstruction (ACLR) in skeletally immature patients is still controversially debated, with several gaps in its literature. More information is needed about the role of concomitant meniscal injuries in postoperative outcomes and return to pre-injury sports level (RTS).
Methods: Fifty skeletally immature patients who underwent ACLR were enrolled prospectively: 21 had meniscal injury additionally, and 29 did not.
J Orthop Res
March 2025
Laboratory for Joint Tissue Repair and Regeneration, Orthopedic Soft Tissue Research Program, The Hospital for Special Surgery, New York, New York, USA.
The tendon graft is known to undergo a remodeling process after anterior cruciate ligament (ACL) reconstruction. However, little is known about the transcriptional profile of this process. The aim of the present study is to identify differentially expressed genes inside the remodeling ACL graft in the early phase after ACL reconstruction in our murine model using RNA sequencing (RNAseq).
View Article and Find Full Text PDFJ Bone Joint Surg Am
March 2025
Department of Sports Medicine, Peking University Third Hospital, Beijing, People's Republic of China.
Background: Identifying patients at high risk for failure of primary anterior cruciate ligament reconstruction (ACLR) on the basis of preoperative magnetic resonance imaging (MRI) measurements has received considerable attention. In this study, we aimed to identify potential risk factors for primary ACLR failure from preoperative MRI measurements and to determine optimal cutoff values for clinical relevance.
Methods: Retrospective review and follow-up were conducted in this nested case-control study of patients who underwent primary single-bundle ACLR using hamstring tendon autograft at our institution from August 2016 to January 2018.
Purpose: To analyze whether magnetic resonance imaging (MRI) can predict return to sport after anterior cruciate ligament (ACL) reconstruction and whether a correlation exists between return to sports, level of activity and MRI signals.
Methods: The search terms selected for inclusion in the title, abstract, and keyword fields were as follows: 'anterior cruciate ligament' OR 'ACL' AND 'graft maturation' OR 'MRI' AND 'return to sport' OR 'sports activity.' For each study, patient data and the MRI protocol used to assess graft maturation were extracted.
Purpose: The purpose of this study was to evaluate patient outcomes following anterior cruciate ligament reconstruction (ACLR) complicated by septic arthritis treated with graft retention versus graft removal protocols. Secondarily, this study aimed to evaluate surgical, demographic and microbial surgical indications for graft retention versus graft removal. We hypothesised that patients who underwent graft removal would have worse outcomes and that patients with septic arthritis caused by more virulent organisms, such as methicillin-resistant or , would be more likely to undergo graft removal.
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