Acinar cell carcinoma of the pancreas (ACCP) is an exceptionally rare malignancy, accounting for <1% of all exocrine pancreatic tumors. This case report describes a 78-year-old male presenting with abdominal pain, weight loss, and anorexia, diagnosed with a tumor in the pancreatic body through imaging and biopsy. The patient underwent a robot-assisted corpo-caudal pancreatectomy and splenectomy using the Da Vinci system. This approach enabled precise resection with minimal blood loss and preservation of critical structures. Histopathology confirmed a well-differentiated acinar cell carcinoma with tumor-free margins. The postoperative course was uneventful, and follow-up imaging at three and six months demonstrated no recurrence or metastasis. This case underscores the advantages of robotic-assisted surgery, including enhanced precision, reduced complications, and optimized recovery, highlighting its role as a transformative tool for managing complex pancreatic tumors like ACCP.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11881696 | PMC |
http://dx.doi.org/10.1093/jscr/rjaf112 | DOI Listing |
Gan To Kagaku Ryoho
February 2025
Dept. of Surgery, Kansai Rosai Hospital.
A 50-year-old female presented with abdominal pain. Upper gastrointestinal endoscopy revealed a 30 mm ulcerative lesion extending from the duodenal bulb to the descending portion, and biopsy confirmed poorly differentiated adenocarcinoma. Abdominal contrast-enhanced CT scan showed an hypovascular tumor in the pancreatic head with suspected invasion into the duodenum, along with enlarged #8 lymph node.
View Article and Find Full Text PDFCells
February 2025
Department of Gastroenterology and Internal Medicine, Medical University of Bialystok, 15-276 Bialystok, Poland.
An association between gut microbiota and the development of pancreatic ductal adenocarcinoma (PDAC) has been previously described. To better understand the bacterial microbiota changes accompanying PDAC promotion and progression stimulated by inflammation and fecal microbiota transplantation (FMT), we investigated stool and pancreatic microbiota by 16s RNA-based metagenomic analysis in mice with inducible acinar transgenic expressions of KrasG12D, and age- and sex-matched control mice that were exposed to inflammatory stimuli and fecal microbiota obtained from mice with PDAC. Time- and inflammatory-dependent stool and pancreatic bacterial composition alterations and stool alpha microbiota diversity reduction were observed only in mice with a Kras mutation that developed advanced pancreatic changes.
View Article and Find Full Text PDFAm J Pathol
March 2025
Section of Pathology, Department of Morphological Biology, Division of Biomedical Sciences, Fukuoka Dental College, Fukuoka, Japan.
Necrotizing sialometaplasia (NSM) is a non-neoplastic lesion listed in the WHO classification of Head and Neck Tumours. In early NSM lesion, there is infarction and necrosis of the acinar cells and squamous metaplasia of the salivary ducts occurs as the lesion matures. Differentiation from squamous cell carcinoma and other malignancies is sometimes required clinically and histopathologically.
View Article and Find Full Text PDFJ Surg Case Rep
March 2025
National Oncology Institute SOLCA Guayaquil, Department of Digestive Surgery, Guayaquil 090505, Ecuador.
Acinar cell carcinoma of the pancreas (ACCP) is an exceptionally rare malignancy, accounting for <1% of all exocrine pancreatic tumors. This case report describes a 78-year-old male presenting with abdominal pain, weight loss, and anorexia, diagnosed with a tumor in the pancreatic body through imaging and biopsy. The patient underwent a robot-assisted corpo-caudal pancreatectomy and splenectomy using the Da Vinci system.
View Article and Find Full Text PDFIntern Emerg Med
March 2025
The Second Department of Gastroenterology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
Acute pancreatitis manifests as an inflammatory condition, starting with the acinar cells in the pancreas and gradually escalating to widespread inflammation. Hypertriglyceridemia ranks as the third leading reason for acute pancreatitis, following gallstones and alcohol use, making up 2-14% of instances [1]. Numerous research findings indicate that acute pancreatitis triggered by hypertriglyceridemia (HTG-AP, hypertriglyceridemic acute pancreatitis) may lead to increased death rates compared to other acute pancreatitis causes hypertriglyceridemia, characterized by fasting serum triglycerides exceeding (150mg/dL; 1.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!