Background: Infection prevention measures are crucial to prevent contamination among frontline healthcare workers (FL-HCWs) and non-frontline healthcare workers (NFL-HCWs). However, these measures can lead to skin lesions, potentially affecting their quality of life.
Objectives: Determine the prevalence of skin lesions caused by infection prevention measures and assess the impact of skin lesions on the quality of life.
Methods: A cross-sectional study was conducted, utilizing a self-administered questionnaire covering demographic and occupational information, self-reported skin lesions, and the Dermatology Life Quality Index (DLQI) for healthcare workers (HCWs) from three medical centres.
Results: Out of the 190 FL-HCWs and 199 NFL-HCWs surveyed, 37.2% reported skin lesions. Female and FL-HCWs exhibited a higher occurrence of skin lesions. Prolonged use of masks was significantly associated with facial skin lesions. While the use of personal protective equipment and hand hygiene had little to no effect on the Dermatology Life Quality Index (DLQI) for 80.7% of healthcare workers (HCWs) with skin lesions, those with facial skin lesions, papules, or a history of any skin lesions, as well as those who more frequently washed their hands, showed a more altered DLQI.
Conclusions: FL-HCWs had more skin symptoms than NFL-HCWs, but these issues were generally not severe and had minimal impact on overall quality of life.
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http://dx.doi.org/10.1177/17571774251324382 | DOI Listing |
Int Med Case Rep J
March 2025
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia.
Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissues, caused by melanized fungi. In cases with extensive cutaneous lesions, heat therapy can be used as an adjuvant to systemic antifungal therapy. This case report aimed to demonstrate the efficacy of heat therapy using an electric heating pad as an adjuvant to itraconazole in the treatment of extensive chromoblastomycosis.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
March 2025
Hospices Civils de Lyon, Hôpital Femme Mère Enfant, Service d'Endocrinologie Pédiatrique et Pédiatrie Générale, Bron, France.
Introduction: McCune-Albright syndrome (MAS) is a rare disease caused by somatic gain-of-function variants in the gene that lead to constitutive activation of the G protein alpha subunit (Gsα). Pathologic consequences can involve several tissues. Fibrous dysplasia (FD), café-au-lait skin macules and hyperfunctioning endocrinopathies are classic manifestations.
View Article and Find Full Text PDFFront Pharmacol
February 2025
Department of Pharmacology, The First People's Hospital of Yancheng, Yancheng, Jiangsu, China.
Background: Ripretinib is a tyrosine kinase inhibitor indicated for the treatment of adult patients with advanced gastrointestinal stromal tumors (GISTs) who have previously received treatment with at least three kinase inhibitors. The objective of this study was to evaluate adverse events(AEs) associated with ripretinib using data from the FDA Adverse Event Reporting System (FAERS) database.
Methods: Individual case safety reports (ICSRs) related to of ripretinib from 2020 Q2 to 2024 Q2 were extracted from the FAERS database.
Acta Derm Venereol
March 2025
Department of Dermatology and Venereology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Chronic pruritus (≥ 6 weeks) is a frequent symptom in atopic diseases, with phenotypes ranging from non-lesional skin to inflammatory diseases like atopic dermatitis. Data on patients' needs and treatment goals depending on the skin phenotype and disease burden are limited. This study aimed to analyse the impact of distinct phenotypes of chronic atopic pruritus on disease burden and treatment goals.
View Article and Find Full Text PDFInt J Mol Sci
March 2025
Department of Clinical Molecular Biology, Medical University of Bialystok, 15-269 Bialystok, Poland.
Mercury is widely used in medicine, agriculture, and industry. Meanwhile, according to the World Health Organization, it has been ranked as one of the ten most hazardous substances in the world, with the Agency for Toxic Substances and Disease Registry ranking it third. It has no known positive functionality in the human body, and even at low concentrations, it can have harmful long-term health effects, seriously affecting the healthcare system as well as posing a serious public health threat.
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