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Predicting response to benralizumab in patients with COPD: a plain language summary of publication of the GALATHEA and TERRANOVA studies.
Ther Adv Respir Dis
March 2025
Late Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
Summary● This is a plain language summary of two articles originally published in and . These articles presented the results of GALATHEA and TERRANOVA, two clinical studies that took place across 41 countries. ○ GALATHEA and TERRANOVA measured how patients' COPD changed from before their first (10, 30, or 100 mg) injection, to after 56 weeks of treatment.
View Article and Find Full Text PDFA study to learn if nirogacestat works and is safe for adult participants with desmoid tumors: a plain language summary of the DeFi study.
Future Oncol
March 2025
hSarcoma Medical Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College, New York, NY, USA.
A plain language summary of the pooled safety results of adalimumab-adbm from the VOLTAIRE clinical trials in people with rheumatoid arthritis, Crohn's disease, and chronic plaque psoriasis.
Expert Opin Biol Ther
March 2025
bBoehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA.
An overview of obesity-related complications: The epidemiological evidence linking body weight and other markers of obesity to adverse health outcomes.
Diabetes Obes Metab
March 2025
Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München, University of Leipzig and University Hospital Leipzig, Leipzig, Germany.
Obesity is a highly prevalent chronic multisystem disease associated with shortened life expectancy due to a number of adverse health outcomes. Epidemiological data link body weight and parameters of central fat distribution to an increasing risk for type 2 diabetes, hypertension, fatty liver diseases, cardiovascular diseases including myocardial infarction, heart failure, atrial fibrillation, stroke, obstructive sleep apnoea, osteoarthritis, mental disorders and some types of cancer. However, the individual risk to develop cardiometabolic and other obesity-related diseases cannot entirely be explained by increased fat mass.
View Article and Find Full Text PDFThe mediating role of health literacy in the relationship between trust in public health authorities and distrust in health systems.
BMC Public Health
March 2025
Faculty of Humanities and Social Sciences, Department of Translation and Interpretation, Ondokuz Mayıs University, Samsun, Turkey.
Background: This study addresses a gap in the literature by examining how health literacy mediates the relationship between trust in public health authorities and distrust in health systems, particularly in the Turkish context. While previous studies have examined trust and health literacy separately, few have examined trust in health systems regarding health literacy and trust in public health authorities. Therefore, the primary purpose of this study is to determine the mediating role of health literacy in the relationship between trust in public health authorities and distrust in the health system.
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