The use of questionnaires in vascular rehabilitation has increased. The Walking Impairment Questionnaire (WIQ) can identify functional risk due to peripheral arterial disease (PAD). This study aimed to assess the accuracy of the WIQ for identifying individuals with PAD and intermittent claudication with low functional capacity. A cross-sectional diagnostic test accuracy study was conducted. The Incremental Shuttle Walk Test (ISWT) assessed the distance walked, and the WIQ, the index test, evaluated the perception of functional capacity. Three reference values in the ISWT were defined: 380 m, 210 m (25th percentile), and 100 m. The accuracy, sensitivity, and specificity of the WIQ were tested using the Receiver Operating Characteristic curve and an alpha of 5% defined statistical significance. One hundred and twenty-one volunteers participated in the study (64 ± 9.7 years, 65% men). The average distance in the ISWT was 270.6 ± 100.2 m. The WIQ scores were: mean 29.7 (14.0-50.2), distance (19; 6.3-47.8), walking speed (25; 13.0-43.5), and stairs (41.7; 12.5-75.0). The WIQ cut-off point for the ISWT references was 1) 37 for 380 m, with a sensitivity of 0.75 and specificity of 0.62 (AUC: 0.73, p=0.003; 95% CI 0.61 to 0.86); 2) 23 for 25th percentile (210 m), with a sensitivity of 0.75 and specificity of 0.70 (AUC: 0.77, p<.0001; 95% CI 0.68 to 0.86) and 3) 14 for 100 m, with a sensitivity of 0.78 and specificity of 0.83 (AUC: 0.77, p=.0001; 95% CI 0.64 to 0.91). The WIQ is helpful as a screening tool in research and clinical practice of PAD. The WIQ score with the best accuracy to identify individuals with low functional capacity was 14.
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http://dx.doi.org/10.1024/0301-1526/a001190 | DOI Listing |
Circ Cardiovasc Imaging
March 2025
Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center and NewYork-Presbyterian Hospital (Y.A.C., M.S., M.C., L.L.J., A.J.E.).
Background: Cardiac diagnostic testing continues to evolve, and controversies remain regarding the optimal utilization of different procedures. We sought to evaluate changes in long-term utilization trends for a wide range of cardiac diagnostic tests in the context of advancing technologies and updated guidelines.
Methods: Annual cardiac testing volumes from 2010 to 2022 in the Medicare Part B population were compared across tests and by provider specialty and analyzed using Joinpoint regression.
Front Allergy
February 2025
Department of Pathology, Microbiology, & Immunology, New York Medical College, Valhalla, NY, United States.
Allergic contact dermatitis (ACD) is an increasingly common skin condition characterized by itchy rashes in response to allergens. The most common diagnostic test involves patch testing (PT), but despite the efficacy of PT for identifying and guiding patients toward avoidance of allergens, PT alone does not elucidate the underlying biomechanistic changes which may be useful for sub-categorizing ACD further. In addition, some patients may never be able to identify their causative allergens unless they go to highly specialized ACD centers.
View Article and Find Full Text PDFBiosaf Health
October 2024
Nanjing Bioengineering (Gene) Technology Center for Medicines, Nanjing 210002, China.
Mpox is a zoonotic disease caused by the monkeypox virus (MPXV). Diagnosing and treating the disease has become a global health concern requiring close attention to its spread to non-endemic regions. Clinical diagnosis is based on laboratory test results.
View Article and Find Full Text PDFJFMS Open Rep
March 2025
Department of Infectious Diseases, University of Georgia, Athens, GA, USA.
Objectives: The objective of this study was to retrospectively assess the pathogens associated with feline ocular and respiratory diseases in routine diagnostic samples submitted to Georgia Veterinary Diagnostic Laboratories. Furthermore, pathogens detected by the respiratory PCR panel in the upper vs lower respiratory tract were compared (specimen separation at pharynx).
Methods: Test records from feline ocular and respiratory PCR panels were collected from 2012 to 2022.
Front Psychol
February 2025
Department of Neurology, Center for Translational and Behavioral Neurosciences, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Risk communication has been found to be a driver of nocebo effects in medical settings by enhancing negative expectations. In fact, merely disclosing the risk of side effects and complications of treatments or medical procedures increases reports of adverse events. Along these lines, it has been proposed that the occurrence of headache after lumbar puncture (LP), a routine diagnostic procedure in neurology, is caused to a large degree by the information delivered by the physician during the informed consent procedure.
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