The relation between total energy intake and the development of ischaemic heart disease was investigated from a review of all available data including the results of 26 years of follow up from a longitudinal study of diet and ischaemic heart disease. A consistent inverse relation was found, whose strength and consistency are similar to those of other established risk factors. It is concluded that there may be a minimum energy intake below which the risk of ischaemic heart disease is increased.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC481825PMC
http://dx.doi.org/10.1136/hrt.53.6.624DOI Listing

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