In the treatment of urinary stones, surgical intervention is crucial. Urinary stones composition and type directly affect surgical planning. However, research on preoperative stone composition analysis is limited. This paper aimed to predict urinary stones types preoperatively using clinical data. Data from 1020 patients, including stone composition, clinical biochemical indicators, and demographic information, were collected. A stone composition graph network was constructed using cosine similarity, with stone composition as nodes and biochemical/demographic data as node features. The Louvain community detection algorithm was utilized to divide the network into distinct communities for the classification of stone types, with the effectiveness of the partitioning evaluated by the Modularity score. Stone types were classified, and their distribution across genders and age groups was described. Clinical feature averages were calculated for each community, and patients were assigned to the most similar community. Six machine learning algorithms (RandomForest, GradientBoosting, SVM, KNN, Logistic Regression, XGBoost) were trained to predict stone types. Model performance was evaluated, and the importance of clinical features for prediction was ranked. Six stone types were identified (Modularity = 0.828), namely common COM (Class I), COM with minor AU (Class II), COM with high UA (Class III), COM containing MAP (Class IV), high CAP-MAP (Class V), and high COM-CAP containing DCPD (Class VI). Among males, Class III and Class I were most prevalent; among females, Class V and Class III were most prevalent (χ = 95.066, P < 0.001). Patients with Class IV stones were significantly older than those with Class I stones (P = 0.038). GradientBoosting showed the best prediction performance, with an Accuracy of 0.837, Precision of 0.840, Recall of 0.8366, F1 Score of 0.8368, and ROC-AUC area of 0.941. Significant clinical features for prediction included urine specific gravity, white blood cells, pH, and crystals. This paper first analyzed stone categories using a community detection algorithm and then predicted types using machine learning, providing a reference for preoperative surgical planning in urinary stones.
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http://dx.doi.org/10.1007/s00240-025-01711-6 | DOI Listing |
Vet Radiol Ultrasound
March 2025
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
In small animal practice, patients often present with urinary lithiasis, and prediction of urolith composition is essential to determine the appropriate treatment. Through abdominal radiographs, the composition of mineral radiopaque uroliths can be determined by considering many different factors; this can be complex and, as such, tailor-made for the use of artificial intelligence (AI). The Minnesota Urolith Center partnered with Hill's Pet Nutrition to develop a deep learning AI algorithm (CALCurad) within a smartphone application called the MN Urolith Application that allows for the preliminary assessment of urolith composition.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Urology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
To identify independent risk factors for urosepsis in diabetic patients with upper urinary tract stones (UUTS) and develop a prediction model to facilitate early detection and diagnosis, we retrospectively reviewed medical records of patients admitted between January 2020 and June 2023. Patients were divided based on the quick Sequential Organ Failure Assessment (qSOFA) score. The least absolute shrinkage and selection operator (LASSO) regression analysis was used for variable selection to form a preliminary model.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Urology, Faculty of Medicine, Cukurova University, 01330, Adana, Turkey.
PCNL, a minimally invasive surgical technique for kidney stone removal, relies on achieving stone-free status, which various scoring systems aim to predict. This study assesses the predictive accuracy of the Clinical Research Office of the Endourological Society (CROES) and Guy's Stone Score (GSS) systems in determining stone-free rates following percutaneous nephrolithotomy (PCNL) in pediatric patients. A retrospective analysis was conducted on 580 pediatric patients who underwent PCNL at Çukurova University Urology Clinic between January 2007 and March 2024.
View Article and Find Full Text PDFUrolithiasis
March 2025
College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, 030801, China.
Kidney stones are a common urological disease. Although there are many ways to treat them, their high recurrence rate remains unresolved. Research has demonstrated that Lysimachia christinae Hance influences kidney stone development; however, the exact mechanism remains unclear.
View Article and Find Full Text PDFArch Iran Med
February 2025
Department of Biostatistics and Epidemiology, University of Social Welfare and Rehabilitation Science, Tehran, Iran.
Background: The incidence of kidney stones has been rising globally, particularly among the elderly. This study aims to determine the prevalence of kidney stones and its associated factors in Iran.
Methods: This cross-sectional study was conducted using the data collected in the first phase of Ardakan Cohort Study on individuals aged 50 years and above, in the Yazd province, Iran.
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