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Mediating effects of gastroesophageal reflux disease and smoking behavior on the relationship between depression and chronic obstructive pulmonary disease: Trans-ethnic Mendelian randomization study.
J Affect Disord
March 2025
Department of Thoracic Surgery, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Suzhou 215101, China. Electronic address:
Background: This study seeks to elucidate the association between depression and the risk of chronic obstructive pulmonary disease (COPD) by Mendelian randomization (MR) analysis, motivated by prior observational studies indicating a potential link between these conditions.
Methods: Data from individuals of European (EUR) and East Asian (EAS) ancestries diagnosed with major depressive disorder (MDD) were selected for analysis. The primary method utilized was inverse variance weighted (IVW) method, supplemented by a series of sensitivity analyses and false discovery rate (FDR) corrections.
Reward prediction-error promotes the neural encoding of episodic learning.
Neuropsychologia
March 2025
Department of Psychology, Institute of Education, China West Normal University, Nanchong 637002.
Reward prediction-error carries significant implications for learning, facilitating the process by influencing prior knowledge and shaping future expectations and decisions. However, the electrophysiological mechanism through which reward prediction-error impacts learning remains incompletely understood. This study aimed to investigate the neural characteristics of reward prediction-error and its effect on recognition memory using Event-Related Potentials (ERPs).
View Article and Find Full Text PDFDiurnal variations of biogenic volatile organic compounds and their role in secondary pollutant formation in the Huai Hong Khrai subtropical forest, Thailand.
Environ Pollut
March 2025
National Astronomical Research Institute of Thailand (Public Organization), Chiang Mai, Thailand; School of Science, Mae Fah Luang University, Chiang Rai, Thailand; Center of Chemical Innovation for Sustainability (CIS), Mae Fah Luang University, Chiang Rai, Thailand. Electronic address:
Understanding the emissions and atmospheric impact of biogenic volatile organic compounds (BVOCs) in subtropical forests remains limited despite their role in secondary pollutant formation. This study presents the first comprehensive BVOC dataset from the Huai Hong Khrai subtropical forest, Northern Thailand, during the dry season (March 4-9, 2024). Using thermal desorption gas chromatography-mass spectrometry (TD-GC-MS), we identified 45 BVOCs, dominated by monoterpenes, sesquiterpenes, and oxygenated derivatives.
View Article and Find Full Text PDFExcitatory and inhibitory neurotransmitter alterations with advancing age and injury in the mouse retina.
Neurobiol Aging
March 2025
Neuroscience and Behavioural Diseases and Eye-ACP, SERI/SNEC, Centre for Vision Research, Duke-NUS Medical School, 8 College Road, 169857, Singapore; Save Sight Institute, University of Sydney, Sydney, NSW, Australia. Electronic address:
Increasing age and elevated intraocular pressure (IOP) are the two major risk factors for glaucoma, the most common cause of irreversible blindness worldwide. Accumulating evidence is pointing to metabolic failure predisposing to neuronal loss with advancing age and IOP injury. Many neurotransmitters are synthesized from endogenous metabolites and are essential for correct cell to cell signaling along the visual pathways.
View Article and Find Full Text PDFCentral Auditory Processing in Children is Affected by Perinatal HIV Exposure.
Pediatr Infect Dis J
March 2025
Department of Paediatrics and Child Health, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.
Background: Children living with HIV are at higher risk for hearing loss compared to children with HIV-unexposed, uninfected (HUU). There is little known regarding the effects of children living with perinatally-acquired HIV (PHIV) and those living with perinatal HIV exposure but uninfected (PHEU) on central auditory function.
Methods: Children aged 11-14 years who were participating in the Auditory Research in Children with HIV study.
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