Fertility results and oncologic outcomes in patients with stage II and III serous borderline ovarian tumors.

This retrospective study aimed to analyze the fertility results and oncologic outcomes of patients with stage II and III serous borderline ovarian tumors after fertility-sparing surgery and to seek future fertility. Among 224 patients with stage II and III serous borderline ovarian tumors treated or referred to our institution, 74 (33%) underwent fertility-sparing surgery. Median time of follow-up was 4.1 years (range; 3.2-7.9); 35 (47%) patients attempted to be pregnant and 21 (60%) had at least 1 pregnancy. Nineteen live-birth pregnancies were observed (9 spontaneously) in 18 patients (all but 1 with non-invasive implants). Seven patients had recurrent disease treated conservatively before pregnancy and 8 recurred after pregnancy (6 recurred as ovarian borderline tumors and 1 as a low-grade serous carcinoma).