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Combination of liquid- and solid-phase extraction followed by achiral and chiral high-performance liquid chromatography as an efficient and sensitive method for determination of panthenol in personal care products.
Int J Cosmet Sci
March 2025
Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava, Slovakia.
Objective: This work deals with the development of an analytical method for the analysis of body milk, cream, and oil. The objective is to develop a reliable, sensitive, and reproducible method suitable to assess the content of dexpanthenol in personal care products and to confirm the declared enantiomeric form.
Methods: Optimization of conditions for the extraction of panthenol from personal care products was carried out for the detection and quantification of panthenol and its enantiomers by achiral and chiral high-performance liquid chromatography (HPLC) with spectrophotometric detection.
The sentinels of coronary artery disease: heterogeneous monocytes.
Front Immunol
March 2025
Jiangxi Cardiovascular Research Institute, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China.
Monocytes are heterogeneous immune cells that play a crucial role in the inflammatory response during atherosclerosis, influencing the progression and outcome of the disease. In the pathogenesis of atherosclerotic diseases, such as coronary artery disease (CAD), monocytes not only serve as the initial sensors of endogenous and exogenous pathogenic factors, but also function as intermediators that bridge the circulatory system and localized lesions. In the bloodstream, heterogeneous monocytes, acting as sentinels, are rapidly recruited to atherosclerotic lesions, where they exhibit a heightened capacity to respond to various pathological stimuli upon detecting signals from damaged vascular endothelial cells.
View Article and Find Full Text PDFRegulation of the immune microenvironment by SUMO in diabetes mellitus.
Front Immunol
March 2025
Department of Endocrinology and Metabolism, Jiujiang Hospital of Traditional Chinese Medicine, Jiujiang, Jiangxi, China.
Post-translational modifications such as SUMOylation are crucial for the functionality and signal transduction of a diverse array of proteins. Analogous to ubiquitination, SUMOylation has garnered significant attention from researchers and has been implicated in the pathogenesis of various human diseases in recent years, such as cancer, neurological lesions, cardiovascular diseases, diabetes mellitus, and so on. The pathogenesis of diabetes, particularly type 1 and type 2 diabetes, has been closely associated with immune dysfunction, which constitutes the primary focus of this review.
View Article and Find Full Text PDFL-serine metabolic regulation and host respiratory homeostasis.
Front Cell Infect Microbiol
March 2025
College of Veterinary Medicine, Southwest University, Chongqing, China.
LSerine, a non-essential amino acid (NEAA), can be obtained through diet or synthesis. Functionally, L-serine not only serves as the precursor of other amino acids, lipids, and nucleotides, but also participates in the folate/methionine cycle. An increasing number of studies have demonstrated that L-serine is widely used in the adjuvant therapy of many diseases (e.
View Article and Find Full Text PDFThe first checklist of alien vascular plants of Kyrgyzstan, with new records and critical evaluation of earlier data. Contribution 3.
Biodivers Data J
March 2025
Altai State University, Barnaul, Russia Altai State University Barnaul Russia.
Background: We continue the series of detailed treatments of alien vascular plants of Kyrgyzstan. The complete background for every species occurrence (herbarium specimens, documented observations, published literature) is uncovered and critically evaluated in a wide context of plant invasions in Central Asia with a reference to Eastern Europe and Northern Asia, based on events in the political and economic history. Complete point distribution maps are provided for each species in Central Asia, in general and Kyrgyzstan, in particular.
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