Acute limb ischemia (ALI) is characterized by a sudden decrease in limb perfusion that threatens the viability of the limb. ALI can result from various causes including arterial embolism, thrombosis, or trauma. The diagnosis is predominantly clinical, guided by the "6 Ps" mnemonic-pain, pallor, pulse deficit, paralysis, paresthesia, and poikilothermia-and confirmed through imaging modalities if needed. Treatment decisions are informed by the Rutherford classification, ranging from viable to irreversibly damaged limbs. Early diagnosis and timely intervention are critical for improving limb salvage and reducing amputation rates.
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http://dx.doi.org/10.1016/j.iccl.2024.11.012 | DOI Listing |
J Int Med Res
March 2025
Healthy Heart Research Center, Heshmat Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Left ventricular thrombus is one of the major complications of dilated cardiomyopathy. Although the presence of a cardiac thrombus is a major risk factor for embolization, several probable conditions, the connection of which is not thoroughly studied, such as gout disease and methamphetamine abuse, are also possible causes. We present the case report of a male in his early 40s with a history of alcohol and methamphetamine abuse, gout, and dilated cardiomyopathy, experiencing multiple ischemic attacks, including acute limb ischemia, dysarthria, and renal infarct.
View Article and Find Full Text PDFFront Pharmacol
February 2025
Department of Intensive Care Unit, Renmin Hospital of Wuhan University, Wuhan, China.
This case report describes a geriatric male patient with myasthenia gravis (MG) secondary to giant thymoma, presenting with progressive muscle weakness and ptosis. The diagnosis of MG was confirmed through pathology, imaging, and laboratory evaluations. Considering the significant surgical risks associated with the giant thymoma, adjuvant chemotherapy was initiated.
View Article and Find Full Text PDFHealthcare (Basel)
February 2025
Occupational Therapy, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC 3086, Australia.
: Chronic pain is common following a stroke and is associated with increased disability. Yet, little is known about the chronic pain experience in the stroke population. This study aimed to identify and explore the features and neuropathic symptoms of chronic pain in individuals with longstanding stroke.
View Article and Find Full Text PDFDiagnostics (Basel)
February 2025
Interventional Radiology Department, AORN "A. Cardarelli", 80131 Naples, Italy.
Deep vein thrombosis (DVT) of the lower extremities, as part of venous thromboembolism disorder, is the third leading cause of acute cardiovascular syndrome after heart attack and stroke. It can result in disability due to pulmonary embolism (PE) and post-thrombotic syndrome (PTS), particularly in cases where the thrombosis extends to the iliofemoral veins. Anticoagulation therapy is effective in preventing thrombus propagation and embolism but may not be sufficient for thrombus degradation and venous patency restoration.
View Article and Find Full Text PDFActa Vet Scand
March 2025
Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Dyrlaegevej 16, Frederiksberg C, DK-1870, Denmark.
Background: Spinal neoplasms are sparsely documented in juvenile dogs. Case reports and small case series have described nephroblastomas, primitive neuroectodermal tumours, gliomas, certain sarcomas, and osteochondromas, but round cell sarcomas have not previously been documented.
Case Presentation: This case report describes a 10-week-old female Rottweiler puppy with acute onset of progressive ataxia and pelvic limb lameness.
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