Acute Limb Ischemia Interventions.

Interv Cardiol Clin

Division of Cardiovascular Medicine, Gill Heart and Vascular Institute, University of Kentucky, 900 South Limestone Street, Suite CTW 320, Lexington, KY 40536, USA. Electronic address:

Published: April 2025

Acute limb ischemia (ALI) is characterized by a sudden decrease in limb perfusion that threatens the viability of the limb. ALI can result from various causes including arterial embolism, thrombosis, or trauma. The diagnosis is predominantly clinical, guided by the "6 Ps" mnemonic-pain, pallor, pulse deficit, paralysis, paresthesia, and poikilothermia-and confirmed through imaging modalities if needed. Treatment decisions are informed by the Rutherford classification, ranging from viable to irreversibly damaged limbs. Early diagnosis and timely intervention are critical for improving limb salvage and reducing amputation rates.

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http://dx.doi.org/10.1016/j.iccl.2024.11.012DOI Listing

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