Chronic limb-threatening ischemia (CLTI) is the end-stage presentation of peripheral artery disease and requires comprehensive care. Despite advancements in treatments, providing timely and equitable care remains challenging. Ongoing research and interdisciplinary collaboration are vital for improving outcomes. Implementing strategies that combine appropriate diagnostics, advanced and innovative revascularization techniques, guideline-directed medical therapies, and efforts to tackle socioeconomic disparities can better address patient needs and enhance quality and quantity of life. This multifaceted approach offers promise for improved long-term outcomes in CLTI patients.
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| http://dx.doi.org/10.1016/j.iccl.2024.11.011 | DOI Listing |
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Pedal acceleration time is related to arterial stiffness in patients with chronic limb-threatening ischemia.
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February 2025
Faculdade Ciências Médicas de Minas Gerais, Belo Horizonte, MG, Brasil.
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Circ Rep
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Department of Vascular Surgery, Asahikawa Medical University Hokkaido Japan.
Background: Acute lower extremity limb ischemia (ALI) is a common vascular surgery emergency, primarily caused by embolism or atherosclerotic in situ thrombosis-acute on chronic limb ischemia (AoCLI). This study aimed to examine the clinical features and treatment challenges of AoCLI.
Methods And Results: Between January 2014 and December 2022, 73 patients with AoCLI (n=35) or embolic ALI (n=38) were analyzed.
Positive Preoperative Stress Test Is Associated With Increased Risk Of Postoperative Myocardial Infarction In Patients Undergoing Aortoiliac Reconstruction For Chronic Limb Threatening Ischemia.
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Center for Learning and Excellence in Vascular and Endovascular Surgery (CLEVER), Department of Surgery, Division of Vascular and Endovascular Surgery, University of California San Diego Health System, San Diego, CA. Electronic address:
Introduction: Aortofemoral or aortoiliac bypasses (AFB/AIB) are considered the gold standard treatment for patients with aortoiliac occlusive disease. Myocardial infarction (MI) is a postoperative risk in AFB/AIB surgeries and preoperative stress testing (PST) is frequently utilized to inform operative planning and pre-operative risk discussions. The aim of this study is to assess the utility of PST in determining outcomes following AFB/AIB in patients with chronic limb threatening ischemia (CLTI).
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Center for Learning and Excellence in Vascular and Endovascular Surgery (CLEVER), Department of Surgery, Division of Vascular and Endovascular Surgery, University of California San Diego Health System, San Diego, CA. Electronic address:
Introduction: This study aims to evaluate perioperative and one-year outcomes of patients undergoing aortobiiliac bypass (ABIB) in comparison with aortobifemoral bypass (ABFB) for the treatment of aortoiliac occlusive disease, using data from the Vascular Quality Initiative (VQI).
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Mice Models for Peripheral Denervation to Enhance Vascular Regeneration.
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March 2025
Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, USA.
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