The femoropopliteal segment is a common anatomic location for peripheral artery disease. The clinical presentation of occlusive disease of the femoropopliteal segment can range from symptomatic or severe claudication if in isolation, or acute or chornic limb threatening ischemia often in the setting of multilevel disease. Patients can be treated with various therapies to improve symptoms and restore perfusion, including medical, exercise, endovascular, and open surgical therapies. The current literature is rapidly evolving on the best management algorithms and strategies based on patient presentation, severity of occlusive disease, and desired therapy goals. This paper summarizes current literature on available medical, endovascular, and surgical therapies for treating peripheral artery occlusive disease of the femoropopliteal segment.
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