Objective: Urinary tract endometriosis affects 0.3-12 % of all cases of endometriosis. Medications have limited efficacy in treating advanced disease. Serous cystadenofibroma is a rare benign variant of ovarian epithelial tumors comprising both epithelial and fibrous stromal components. Its diagnosis is challenging due to its visual resemblance to malignancy.
Case Report: A patient diagnosed with ureteral endometriosis underwent surgical excision of the right kidney and ureter. Ten years later, the patient developed a tumor suspected to be malignant at the same site. Following exploratory laparotomy, the tumor was pathologically diagnosed as resembling serous cystadenofibroma.
Conclusion: Differentiating a such tumors from other malignancies based solely on imaging findings is challenging. It is crucial to judge the degree of surgical intervention through intraoperative macroscopic examination and rapid pathological assessment. The efficacy of gonadotropin-releasing hormone analog (GnRHa) and dienogest (DNG) therapy in preventing the recurrence of such tumors following surgery for endometriosis remains uncertain.
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http://dx.doi.org/10.1016/j.tjog.2024.12.014 | DOI Listing |
Front Immunol
March 2025
Laboratory of Translational Medicine Research, Deyang People's Hospital of Chengdu University of Traditional Chinese Medicine, Deyang, China.
Tissue-resident memory T (T) cells are a specialized subset of memory T cells that permanently reside in non-lymphoid tissues, providing localized and long-lasting immune protection. In the urinary tract, T cells play critical roles in defending against infections, mediating tumor immunity, and influencing the pathogenesis of chronic inflammatory diseases. Their therapeutic potential is immense, with promising avenues for vaccine development, enhanced cancer immunotherapy, and targeted treatments for chronic inflammation.
View Article and Find Full Text PDFCureus
February 2025
Department of Urology, Rush University Medical Center, Chicago, USA.
Urachal cystadenocarcinoma (UC) is a rare but highly aggressive subtype of bladder cancer. While most localized cases of UC are asymptomatic, occasionally, patients present with nonspecific lower urinary tract symptoms. Unfortunately, most cases are not detected until advanced disease is present.
View Article and Find Full Text PDFCureus
February 2025
Internal Medicine, Cape Fear Valley Health, Fayetteville, USA.
Chronic Foley catheter use significantly increases the risk of scrotal abscesses, particularly in patients with comorbidities that impair immune function, such as diabetes and chronic kidney disease (CKD). We report a case of a 56-year-old male with type II diabetes, CKD, and a chronic indwelling Foley catheter who presented with progressive scrotal swelling and pain. Cultures identified and from both urine and abscess fluid, confirming a possible urinary tract infection (UTI) as the source of scrotal abscess.
View Article and Find Full Text PDFJ Korean Med Sci
March 2025
Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Background: Differentiating between asymptomatic bacteriuria (ASB) and urinary tract infection (UTI) is difficult in patients who have difficulty communicating their symptoms. This study aimed to evaluate the diagnostic accuracy of urine leukocytes in distinguishing between UTI and ASB, and the clinical outcomes of patients with UTI according to the degree of pyuria.
Methods: This retrospective cohort study included patients with positive urine cultures between July 2022 and June 2023 at two hospitals.
J Cell Biochem
March 2025
Stem Cell Laboratory, Department of Biotechnology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
Glomerular filtration function and homeostasis are largely due to the cross-talk between podocytes, endothelial cells, and mesangial cells (MCs). Any disturbance in this association causes glomerular diseases (GD). Cell-based therapies are the best option in the treatment of GD.
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