To investigate the clinical characteristics and treatment outcomes of patients with blast-induced hearing loss(BIHL). The clinical features, laboratory parameters, audiometric profiles, and treatment efficacy of patients with blast induced hearing loss and those with idiopathic sudden hearing loss(ISHL) were analyzed using t-tests, Wilcoxon rank-sum tests, and chi-square tests, with a significance level set at <0.05. A total of 59 patients in the BIHL group and 117 patients in the ISHL group were included in this study. The mean age of the BIHL group was(39.07±14.49) years, comprising 45 males and 14 females. After the blast, 21 patients went to the hospital within the initial 14-day period, and an additional 38 patients seeking admission thereafter. In the BIHL group, 33 patients had unilateral hearing loss with PTA of (50.30±28.85) dB HL, while 26 had bilateral hearing loss with a PTA of(44.54±26.22) dB HL. In comparison, among the ISHL group, 112 patients had unilateral hearing loss with a PTA of(56.28±14.19) dB HL, and 5 had bilateral involvement with a PTA of(56.25±35.14) dB HL. The effective treatment rate within 14 days for the BIHL group was 31.8%, while for the ISHL group, the effective rate within 14 days was 77.0%. Blast-induced hearing loss is caused by exposure to high-intensity noise. The overall treatment effectiveness during hospitalization is lower compared to idiopathic sudden hearing loss, and the treatment window is shorter. Therefore, greater emphasis should be placed on prevention.
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http://dx.doi.org/10.13201/j.issn.2096-7993.2025.03.008 | DOI Listing |
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
March 2025
To investigate the clinical characteristics and treatment outcomes of patients with blast-induced hearing loss(BIHL). The clinical features, laboratory parameters, audiometric profiles, and treatment efficacy of patients with blast induced hearing loss and those with idiopathic sudden hearing loss(ISHL) were analyzed using t-tests, Wilcoxon rank-sum tests, and chi-square tests, with a significance level set at <0.05.
View Article and Find Full Text PDFMil Med
March 2025
Defence Research and Development Canada, Toronto Research Centre, Toronto, ON M3K 2C9, Canada.
Introduction: Occupational trades expose military service members to unique sound exposure profiles, distinct in frequency and amplitude to those commonly studied in industrial settings. Characteristics of the energy exposure incurred through blast exposure exercises a distinct mechanism of injury in the auditory system that yield acute and cumulative health impacts. The following paper considers physiological and self-reported data attributed to repeated low-level blast exposure.
View Article and Find Full Text PDFImmun Inflamm Dis
January 2025
Department of Medical Biochemistry, Institute of Health, Dambi Dollo University, Dambi Dolo, Ethiopia.
Background: The pathomechanism of blast traumatic brain injury (TBI) and blunt TBI is different. In blast injury, evidence indicates that a single blast exposure can often manifest long-term neurological impairments. However, its pathomechanism is still elusive, and treatments have been symptomatic.
View Article and Find Full Text PDFAnn Biomed Eng
March 2025
School of Biomedical Engineering, University of Oklahoma, Norman, OK, 73019, USA.
Mil Med
August 2024
School of Aerospace and Mechanical Engineering, University of Oklahoma, Norman, OK 73019, USA.
Introduction: Auditory injuries induced by repeated exposures to blasts reduce the operational performance capability and the life quality of military personnel. The treatment for blast-induced progressive hearing damage is lacking. We have recently investigated the therapeutic function of liraglutide, a glucagon-like peptide-1 receptor agonist, to mitigate blast-induced hearing damage in the animal model of chinchilla, under different blast intensities, wearing earplugs (EPs) or not during blasts, and drug-treatment plan.
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