In recent years, the macro-micro structure (servo platform for macro motion and galvanometer for micro motion) composed of a galvanometer and servo platform has been gradually applied to laser processing in order to address the increasing demand for high-speed, high-precision, and large-format precision machining. The research in this field has evolved from step-and-scan methods to linkage processing methods. Nevertheless, the existing linkage processing methods cannot make full use of the field-of-view (FOV) of the galvanometer. In terms of motion distribution, the existing methods are not suitable for continuous micro segments and generate the problem that the distribution parameter can only be obtained through experience or multiple experiments. In this research, a new laser linkage processing method for global trajectory smoothing of densely discretized paths is proposed. The proposed method can generate a smooth trajectory of the servo platform with bounded acceleration by the finite impulse response (FIR) filter under the global blending error constrained by the galvanometer FOV. Moreover, the trajectory of the galvanometer is generated by vector subtraction, and the motion distribution of macro-micro structure is accurately realized. Experimental verification is carried out on an experimental platform composed of a three-axis servo platform, a galvanometer, and a laser. Simulation experiment results indicate that the processing efficiency of the proposed method is improved by 79% compared with the servo platform processing only and 55% compared with the previous linkage processing method. Furthermore, the method can be successfully utilized on experimental platforms with good tracking performance. In summary, the proposed method adeptly balances efficiency and quality, rendering it particularly suitable for laser precision machining applications.
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http://dx.doi.org/10.3390/mi16020177 | DOI Listing |
Orthop Surg
March 2025
Department of Orthopaedic Surgery and Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Recent literature has increasingly demonstrated the significant function of autonomic nerves in regulating physiological and pathological changes associated with the skeletal system. Extensive studies have been conducted to understand the contribution of the autonomic nervous system (ANS) to skeletal metabolic homeostasis and resistance to aseptic inflammation, specifically from the viewpoint of skeletal neurobiology. There have been plenty of studies on how the sympathetic nervous system (SNS) and parasympathetic nervous system (PNS), the two main branches of the ANS, regulate bone remodeling, which is the process of bone formation and resorption.
View Article and Find Full Text PDFSoft Matter
March 2025
Department of Chemistry "Ugo Schiff" and CSGI, University of Florence, via della Lastruccia 3, Sesto Fiorentino, Florence, Italy.
Polyurethanes are largely employed in various fields such as building, insulation and adhesive industries, but there is the constant need to develop sustainable formulations using "green" components and feasible processes. Here, a new series of sustainable castor oil and epoxidized castor oil-based (CO/EpCO) polyurethane networks was synthetized and characterized. The added epoxy functions react with isocyanates forming oxazolidinone linkages in the gels' network, reducing the gelation time from over 3 hours up to 0.
View Article and Find Full Text PDFBioinformatics
March 2025
Department of Biology, Lund University, Lund, 22 362, Sweden.
Summary: PopGLen is a Snakemake workflow for performing population genomic analyses within a genotype-likelihood framework, integrating steps for raw sequence processing of both historical and modern DNA, quality control, multiple filtering schemes, and population genomic analysis. Currently, the population genomic analyses included allow for estimating linkage disequilibrium, kinship, genetic diversity, genetic differentiation, population structure, inbreeding, and allele frequencies. Through Snakemake, it is highly scalable, and all steps of the workflow are automated, with results compiled into an HTML report.
View Article and Find Full Text PDFChem Sci
March 2025
George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry, University of Florida Gainesville Florida 32611 USA
Thin films formed by complexation of oppositely charged polyelectrolytes have significant potential in applications such as separation membranes, biocompatible or anticorrosion coatings, and drug delivery systems. While layer-by-layer deposition is a reliable method for producing conformal films, this multi-step process limits scalability. In this study, we functionalize polymers with photoactive protecting and crosslinking groups, allowing a one-step approach for preparing polyelectrolyte complex (PEC) films.
View Article and Find Full Text PDFOrg Biomol Chem
March 2025
Department of Organic Synthesis and Process Chemistry, CSIR-Indian Institute of Chemical Technology, Uppal Road, Hyderabad-500007, India.
Herein, we developed an efficient chemical synthetic strategy of a tetrasaccharide repeating unit corresponding to the K141 type capsular polysaccharide of KZ1106. The synthesis of the propylamine-linked tetrasaccharide is executed through an efficient [2 + 2] block glycosylation strategy. The construction of a synthetically challenging β-L-rhamnopyranosyl linkage was achieved through 'armed-disarmed' glycosylation, with the assistance of a picolinoyl group located remotely through the hydrogen bond mediation effect.
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