Magnetic Polymeric Conduits in Biomedical Applications.

Micromachines (Basel)

Department of Chemistry, Bar-Ilan Institute for Nanotechnology and Advanced Materials (BINA), Bar-Ilan University, Ramat-Gan 5290002, Israel.

Published: January 2025

Magnetic polymeric conduits are developing as revolutionary materials in regenerative medicine, providing exceptional benefits in directing tissue healing, improving targeted medication administration, and facilitating remote control via external magnetic fields. The present article offers a thorough examination of current progress in the design, construction, and functionalization of these hybrid systems. The integration of magnetic nanoparticles into polymeric matrices confers distinctive features, including regulated alignment, improved cellular motility, and targeted medicinal delivery, while preserving structural integrity. Moreover, the incorporation of multifunctional attributes, such as electrical conductivity for cerebral stimulation and optical characteristics for real-time imaging, expands their range of applications. Essential studies indicate that the dimensions, morphology, surface chemistry, and composition of magnetic nanoparticles significantly affect their biocompatibility, degrading characteristics, and overall efficacy. Notwithstanding considerable advancements, issues concerning long-term biocompatibility, biodegradability, and scalability persist, in addition to the must for uniform regulatory frameworks to facilitate clinical translation. Progress in additive manufacturing and nanotechnology is overcoming these obstacles, facilitating the creation of dynamic and adaptive conduit structures designed for particular biomedical requirements. Magnetic polymeric conduits, by integrating usefulness and safety, are set to transform regenerative therapies, presenting a new avenue for customized medicine and advanced healthcare solutions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11857720PMC
http://dx.doi.org/10.3390/mi16020174DOI Listing

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