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Late-Onset Urticarial and Erythema Multiforme-Like Eruption Following SARS-CoV-2 Infection.
Cureus
February 2025
Dermatology, Grand Strand Medical Center, Myrtle Beach, USA.
Although SARS-CoV-2 primarily targets the upper respiratory system, its evolving clinical profile has revealed a diverse range of manifestations across multiple organ systems. Emerging evidence increasingly highlights various skin manifestations associated with the virus. This report details the case of a patient who developed a rapidly progressive urticarial dermatosis, characterized by both urticarial and erythema multiforme-like features, five weeks after a SARS-CoV-2 infection.
View Article and Find Full Text PDFSevere Hypersensitivity Reactions with Oral Manifestations: Case Reports on Stevens-Johnson Syndrome and DRESS Syndrome.
J Pharm Bioallied Sci
December 2024
Department of Diagnostic and Surgical Dental Sciences, College of Dentistry/Gulf Medical University, Ajman, UAE.
Stevens-Johnson syndrome (SJS) and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome are rare conditions, representing severe hypersensitivity reactions with significant oral presentations. SJS is an uncommon but severe variant of erythema multiforme, presenting skin and mucosal eruptions that can be potentially fatal. DRESS syndrome, similarly, involves a severe hypersensitivity reaction characterized by fever, rash, and organ involvement.
View Article and Find Full Text PDFObjectives: Systemic Lupus Erythematosus (SLE) can cause oral mucosal lesions, it is a severe autoimmune disease, manifesting as variable kinds of oral lesions. Occasionally, these clinical manifestations maybe be misdiagnosed as other diseases. The aim of the present article is to report a rare case of SLE oral mucosa lesions masquerading as an Erythema multiforme (EM) oral lesions in a young man.
View Article and Find Full Text PDFErythema multiforme major presenting in a teenager with anti-N-Methyl-D-Aspartate receptor encephalitis.
Ital J Dermatol Venerol
March 2025
Unit of Dermatology Clinic, IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy.
Targeting the Galectin-7/TRPM2/Zn/DRP-1 Signaling Pathway: A Potential Therapeutic Intervention in the Pathogenesis of SJS/TEN.
Allergy
March 2025
Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) represent a spectrum of severe drug-induced cutaneous reactions. These conditions are characterized by widespread and confluent keratinocyte apoptosis, which differentiates them from erythema multiforme (EM). Mounting evidence has implicated the mitochondrial-dependent apoptosis pathway in the pathogenesis of SJS/TEN, but the potential roles and specific mechanisms of these pathways in SJS/TEN remain largely unexplored.
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