Purpose: To conduct a comprehensive umbrella review to synthesise existing evidence and critically evaluate the significance of keratinised mucosa width in peri-implant health and assess the consistency and heterogeneity among previous systematic reviews on this topic.
Materials And Methods: A comprehensive search strategy was implemented across multiple databases. Eligible studies were screened and data were extracted. Methodological quality was assessed using A MeaSurement Tool to Assess systematic Reviews version 2, and strength of evidence was evaluated using the Grading of Recommendations Assessment, Development and Evaluation criteria. A meta-meta-analysis using Hedges' g as the effect size measure was performed to investigate the outcomes of implant therapy in patients with (control) and without adequate keratinised mucosa width (case).
Results: Ten systematic reviews, published between 2012 and 2023, were included. Significant effect sizes were found for mucosal recession, Gingival Index/modified Gingival Index, modified Plaque Index and marginal bone loss. Specifically, narrow keratinised mucosa width ( 2 mm) was associated with increased mucosal recession (equivalent odds ratio 4.05, P = 0.03), higher Gingival Index/modified Gingival Index scores (equivalent odds ratio 3.131, P = 0.001), elevated modified Plaque Index scores (equivalent odds ratio 5.34, P = 0.005) and greater marginal bone loss (equivalent odds ratio 1.852, P = 0.0007). No significant associations were observed for bleeding on probing, pocket depth changes or pocket depth values. Follow-up time did not have a significant effect on these outcomes.
Conclusions: Inadequate keratinised mucosa width ( 2 mm) correlated with increased mucosal recession, higher Gingival Index/modified Gingival Index, Plaque Index/modified Plaque Index scores and greater marginal bone loss. However, there is still a lack of sufficient evidence indicating the impact on bleeding on probing, pocket depth, implant survival and disease prevalence (no significant association or insufficient evidence).
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Gingival odontogenic keratocyst presenting as pseudoinfection: Inclusion of demonstrative case report and review.
Clin Adv Periodontics
March 2025
Department of Oncology and Diagnostic Sciences, University of Maryland School of Dentistry, Baltimore, Maryland, USA.
Background: The peripheral odontogenic keratocyst (POKC) is a rare developmental odontogenic cyst and represents the soft tissue counterpart of the more common intraosseous variant. Although the majority of POKCs have been discovered on the gingiva, scant information is available in the periodontal literature.
Methods: A 69-year-old man presented with a painless, red fluctuant-like papular lesion on the maxillary anterior labial gingiva.
The relationship between adequate keratinized mucosa and peri-implant disease: a systematic review and meta-analysis.
BMC Oral Health
March 2025
Department of Stomatology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, 100020, China.
Background: Controversial conclusions have been drawn from recent researches that examined the impact of keratinized mucosa width on clinical parameters of peri-implant health status. The purpose of this meta-analysis is to assess the effect of keratinized mucosa width on these clinical parameters by combining data from different studies.
Methods: A systematic literature search was performed using PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and VIP Data from the beginning of the database until May 2024.
Background: The treatment of advanced peri-implantitis-related bone defects is often associated with ineffective efforts to halt disease progression. The objective of this case series was to evaluate the performance of reconstructive therapy for the management of advanced peri-implantitis using recombinant human platelet-derived growth factor-BB as an adjunctive biological agent.
Materials And Methods: A prospective case series study on advanced intrabony peri-implantitis bone defects (≥ 50% bone loss) was performed.
Purpose: To conduct a comprehensive umbrella review to synthesise existing evidence and critically evaluate the significance of keratinised mucosa width in peri-implant health and assess the consistency and heterogeneity among previous systematic reviews on this topic.
Materials And Methods: A comprehensive search strategy was implemented across multiple databases. Eligible studies were screened and data were extracted.
Structure, biology, and function of peri-implant soft tissues in health and disease: a comprehensive review of the literature.
J Periodontal Implant Sci
January 2025
Faculty of Dentistry, Universidad Santo Tomas de Aquino, Bucaramanga, Colombia.
The morphogenesis of peri-implant soft tissues following surgical trauma, along with the nature, topography, and design of implant-prosthetic material surfaces, leads to peri-implant tissues that exhibit unique histological and morphological characteristics. It has been shown that mucosal phenotypes with a mucosal thickness of at least 2 mm and a keratinised mucosa width of at least 2 mm promote proper integration and a biological seal at the mucosa-implant interface. This seal prevents pathogen penetration, protects the underlying peri-implant bone, and reduces susceptibility to inflammatory peri-implant diseases (IPDs).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!