Purpose: Advancements in anterior segment imaging have significantly improved the precision of corneal diagnostics, aiding ocular conditions management. The study evaluated the agreement between two Scheimpflug devices-Pentacam and Remidio Visionix 650 (VX650)-in assessing corneal and anterior chamber parameters in patients with and without corneal abnormalities.
Materials And Methods: This prospective study at a tertiary eye care hospital measured pachymetry values (central corneal thickness, thinnest point), front corneal surface parameters (keratometry, curvature, astigmatism), back corneal surface parameters (elevation, curvature) and anterior chamber parameters (depth, volume, angle). Bland-Altman analysis assessed agreement between the devices, and the Intraclass Correlation Coefficient (ICC) evaluated VX650's repeatability.
Results: Of the 202 patients (mean age was 25 ± 4.33 years), 141 eyes were classified as normal and 61 as abnormal (41 keratoconus, 17 post-LASIK, 3 post-ICL). Bland-Altman analysis showed good agreement between Pentacam and VX650 for anterior segment parameters. The VX650 measured marginally thicker corneal thickness (mean difference of central corneal thickness (CCT) of -4.0 ± 6.3 µm). Statistically significant differences in apical corneal thickness were noted for post-refractive surgery patients. K1 and K2 values showed significant variations in keratoconus but were not clinically significant. Anterior chamber depth was similar between devices, though volume differences were observed post-surgery. ICC indicated good to excellent repeatability (above 0.75) for most parameters.
Conclusion: Remidio Visionix VX650 showed good agreement with Pentacam for key anterior segment measurements, confirming its reliability for corneal diagnostics. Additionally, its multifunctional capabilities offer potential for streamlining workflows, especially in clinics seeking efficient, comprehensive eye assessments.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879984 | PMC |
| http://dx.doi.org/10.3389/fopht.2025.1516423 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Bilateral intraocular choristoma in a 2-day-old foal.
J Vet Diagn Invest
March 2025
Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA.
A 2-d-old Warmblood colt was submitted for autopsy with a spectrum of bilateral ocular abnormalities. At postmortem examination, a constellation of lesions within the anterior segment included retention of ectodermal elements, compatible with choristoma. Ocular choristomas can be localized to different intraocular structures and are rare in equids.
View Article and Find Full Text PDFQuantifying anterior segment vascular changes in thyroid eye disease using optical coherence tomography angiography.
BMC Med Imaging
March 2025
Ophthalmology Department and Eye Research Center, Farabi Eye Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Purpose: Thyroid eye disease (TED) presents challenges in the accurate assessment of disease activity, especially concerning ocular surface manifestations. This study aims to evaluate the potential of anterior segment optical coherence tomography angiography (AS-OCTA) in quantifying vascular changes associated with TED, thereby enhancing understanding of its pathophysiology and aiding in diagnosis and management.
Methods: We conducted a cross-sectional study involving 29 TED patients and 21 healthy controls.
The cranial base and midface characteristics in apert and Crouzon syndrome: A 3-dimensional analysis of morphological variations.
J Craniomaxillofac Surg
March 2025
Mathematics Division, Centre for Foundation Studies in Science, Universiti Malaya, Malaysia; Center for Data Analytics Consultancy and Services, Faculty of Science, Universiti Malaya, Malaysia. Electronic address:
The craniofacial morphology in patients with syndromic craniosynostosis varies from one spectrum to another. Our study aims to explore the craniofacial morphology and growth pattern in patients with Apert and Crouzon syndrome. This study involved 39 computed tomographic scans of skull (Apert = 11, Crouzon = 10, Control = 18), divided into 2 age subgroups.
View Article and Find Full Text PDFWhole-brain mapping in adult zebrafish and identification of the functional brain network underlying the novel tank test.
eNeuro
March 2025
Department of Biological Sciences, Wayne State University, Detroit, MI 48202.
Zebrafish have gained prominence as a model organism in neuroscience over the past several decades, generating key insight into the development and functioning of the vertebrate brain. However, techniques for whole brain mapping in adult stage zebrafish are lacking. Here, we describe a pipeline built using open-source tools for whole-brain activity mapping in adult zebrafish.
View Article and Find Full Text PDFUnderestimation of Follow-Up Infarct Volume by Acute CT Perfusion Imaging.
Neurology
April 2025
Leuven Brain Institute, Department of Neurosciences, Experimental Neurology, KU Leuven-University of Leuven, Belgium.
Background And Objectives: It is unknown whether acute CT perfusion (CTP) core imaging may underestimate the follow-up infarct. We hypothesize that infarct underestimation occurs especially in late-presenting patients and that underestimated infarct can partially be detected on baseline noncontrast CT (NCCT).
Methods: We included patients with acute anterior circulation ischemic stroke who underwent baseline NCCT and CTP imaging, complete endovascular reperfusion, and follow-up MRI from the Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke (DEFUSE 3) trial and a consecutive, monocenter cohort.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!