Pulmonary hamartomas are the most common benign tumors of the lung in adults. They are usually asymptomatic because of their small size and their slow-growing character. We report the case of a 5-year-old child presenting with a giant lung mass causing recurrent right pneumonia. Surgical resection with middle lobectomy was performed. Final histology revealed pulmonary hamartoma with predominant adenofibromatous and lipomatous differentiation.
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http://dx.doi.org/10.12688/f1000research.146993.2 | DOI Listing |
Rheumatology (Oxford)
March 2025
Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
The plenary session on "End organ damage and repair" at the 21st International Vasculitis Workshop Congress featured two lectures and three studies addressing the pathogenesis, diagnosis, and management of fibrosis in vasculitis. The studies presented at the session demonstrate the importance of cellular interplay in driving inflammation and fibrosis, like the B cell-fibroblast interactions in the aorta of giant cell arteritis patients and the potential fibrotic role of specific infiltrating macrophage subtypes in ANCA-associated glomerulonephritis. Moreover, organ damage, such as the presence of interstitial lung disease in ANCA-associated vasculitis, may impact on long-term outcome, and need a personalized treatment approach.
View Article and Find Full Text PDFCureus
February 2025
Thoracic Surgery, Mohammed VI University Hospital, Marrakesh, MAR.
Solitary fibrous tumor of the pleura (SFTP) is a rare mesenchymal tumor, making up a small fraction of primary pleural tumors. It is typically benign but can display malignant features. This case presents a 59-year-old patient with a giant malignant SFTP located in the right posterior inferior mediastinum, which caused significant compression of adjacent structures, including the lung, heart, and esophagus.
View Article and Find Full Text PDFJ Cardiovasc Magn Reson
March 2025
Adult Congenital Heart Disease Department, Guy's and St Thomas' NHS Foundation Trust, Westminster Bridge Rd, London SE1 7EH, United Kingdom; Cardiovascular Imaging Department, King's College, London, United Kingdom.
Background: Main pulmonary artery (mPA) dilatation has been reported in patients with isolated pulmonary valve (PV) stenosis. The aim of our study was to detect the incidence of mPA dilatation and aneurysm in patients with isolated PV stenosis and the association with PV function.
Methods: In this single-centre retrospective observational study all patients with a diagnosis of isolated PV stenosis referred to our centre were enrolled.
Pulmonary hamartomas are the most common benign tumors of the lung in adults. They are usually asymptomatic because of their small size and their slow-growing character. We report the case of a 5-year-old child presenting with a giant lung mass causing recurrent right pneumonia.
View Article and Find Full Text PDFPathol Oncol Res
March 2025
Oxford Sarcoma Service, Nuffield Orthopaedic Centre, Oxford, England, United Kingdom.
Giant cell tumour of bone (GCTB) is viewed as a benign, locally aggressive primary bone tumour with metastatic potential. Current management is surgery with bone curettage or resection and systemic therapy with denosumab. Diagnosis is confirmed histologically prior to surgery, with staging for pulmonary disease, as pulmonary metastases (PM) reportedly occur in <8%.
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