Introduction: With the ever-increasing demand for laparoscopic hernia repair, it is important to scrutinise the benefit in terms of recurrence, pain and cosmesis with the open technique for small ventral hernias. The objective is to compare the outcomes of open and laparoscopic intraperitoneal onlay mesh (IPOM) repair for small ventral hernias (defect size <3 cm).
Patients And Methods: A prospective analysis of patients who underwent surgical mesh repair for ventral hernias with defects smaller than 3 cm between January 2021 and September 2022. Ventral patch composite mesh (VentralexTM) and composite Prolene-cellulose mesh (ProceedTM) were utilised. We collected and analysed patient characteristics, operative findings and post-operative data, including recurrence rates, pain scores and cosmetic satisfaction over a 12-month follow-up period.
Results: Among the 116 patients included in the study, 54 underwent laparoscopic IPOM repair, while 62 underwent open IPOM repair. The laparoscopic group had an average hernia defect size of 2.7 cm (±0.3), while for the open repair group, it was 2.4 cm (±0.4). The duration of open repair was notably shorter than that of laparoscopic repair (54 min [±16] vs. 94 min [±27]; P = 0.001). Postoperatively, there were significant differences between the groups in terms of VAS scale pain score on post-operative day 1 ([7 ± 2 vs. 4 ± 2]; P = 0.008). Eight cases developed surgical site infections requiring oral antibiotics in the open group, whereas the laparoscopic group had 3 cases (P = 0.6).
Conclusion: Open IPOM repair can be considered as a favourable option for ventral hernias <3 cm when compared to laparoscopic IPOM repair, primarily due to its shorter operative time, ease of spinal anaesthesia, single incision, shorter learning curve and absence of risks associated with port-site hernias. Higher initial pain in the laparoscopic group can be attributed to the use of absorbable tacks and transfascial sutures. No discernible disparities were observed in terms of chronic pain or recurrence rates between these surgical approaches.
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http://dx.doi.org/10.4103/jmas.jmas_247_24 | DOI Listing |
J Eukaryot Microbiol
March 2025
Institute for Comparative Genomics, and Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
Ancyromonadida is a taxon of small heterotrophic flagellates occupying an unresolved but deep-branching position in the eukaryotic tree of life, thus suspected to be important to studies of early eukaryotic evolutionary relationships and the characteristics of the last eukaryotic common ancestor. Sampling and cultivation of the full diversity of ancyromonad species are therefore areas of considerable interest. Ancyromonas melba is a species originally described from hypersaline material for which no monoprotistan culture or molecular data have been available, but whose distinct morphology suggests it may represent a new major lineage within Ancyromonadida.
View Article and Find Full Text PDFProg Neuropsychopharmacol Biol Psychiatry
March 2025
Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China. Electronic address:
Evidence suggests that neurovascular coupling (NVC) dysfunction in cerebral small vessel disease (CSVD) may precede typical clinical and imaging manifestations. Here, we explored the underlying brain alterations of multiscale networks in CSVD patients related to cognitive impairment based on the method of NVC. We investigated 124 CSVD patients, including 70 patients with mild cognitive impairment (MCI) and 54 patients with no cognitive impairment (NCI).
View Article and Find Full Text PDFIntroduction This study aimed to evaluate the initial outcomes of a novel transfixing uretero-enteral anastomosis technique in robot-assisted radical cystectomy (RARC) with ileal conduit in an intracorporeal urinary diversion (ICUD), focusing on its potential to reducing the incidence of uretero-enteric anastomotic stricture (UEAS). Methods The study subject is 11 patients who underwent RARC and ileal conduit created as an ICUD at a single cancer center between 2022 and 2024. The technique involved opening the ventral side of the oral end of the separated ileum approximately 5 cm apart.
View Article and Find Full Text PDFJ Neurosurg
March 2025
2Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville.
Objective: Essential tremor (ET) is a prevalent movement disorder that also includes nonmotor symptoms such as anxiety, depression, and cognitive impairment. Deep brain stimulation (DBS) is an established treatment for ET, yet its impact on nonmotor symptoms remains unclear. This study aims to describe neuropsychological outcomes following ventral intermediate nucleus (VIM) DBS in a large cohort of patients with ET and identify factors associated with changes in depression and cognitive function.
View Article and Find Full Text PDFNeuroradiology
March 2025
Department of Radiology, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing, 400016, China.
Purpose: This study aimed to investigate thalamic microstructural alterations in cerebral small vessel disease (CSVD) patients with mild cognitive impairment (MCI) using diffusion kurtosis imaging (DKI), and to examine the associations between DKI parameters and cognitive performance.
Methods: The study included 80 CSVD patients and 40 healthy controls (HC). Based on Montreal Cognitive Assessment (MoCA) scores, CSVD patients were divided into MCI (n = 40) and non-MCI (n = 40) groups.
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