Objectives: We aimed to investigate the common mechanisms in restless legs syndrome (RLS) and overactive bladder (OAB), the prevalence of OAB in RLS, and the effects of RLS treatment on OAB.
Methods: Sixty patients newly diagnosed with RLS and 60 healthy individuals in the control group were included in the study. The patients completed the RLS-Severity Rating Scale and were started on pramipexole for treatment. Patients diagnosed with RLS were examined by the same physician for differential diagnosis, and urinalysis, urination diary, and ultrasonography were performed. All patients completed the AAM-V8 form, validated in Turkish, before and after treatment. The treatment effectiveness of the drug on the patients was evaluated using questioning forms.
Results: No statistically significant difference was detected between gender and the average age of the patients and the control group (p = 0.540, p = 0.056). In the evaluation, a statistically higher rate of OAB was detected in the RLS group than in the control group (33.3%-13.3%, p < 0.01) and a positive correlation was observed between the severity of RLS symptoms and OAB-V8 scores. After RLS treatment, a statistically significant improvement was observed in the patients' OAB symptom scores compared to before treatment (p < 0.001).
Conclusions: Our study revealed that the prevalence of OAB is higher in RLS than in the control group. Dopamine agonists used in the treatment of RLS may be useful as an alternative treatment option in the treatment of OAB, especially in certain patient groups who do not respond to standard treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/iju.70036 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Effect of intermittent hemodialysis filtration mode on intradialytic hypotension and nutritional status in patients with end-stage renal disease.
Ther Apher Dial
March 2025
Nephrology Blood Purification Center, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Introduction: This study aimed to investigate the effect of intermittent hemodialysis filtration mode (IHDF) on intradialytic hypotension and nutritional status in patients with end-stage renal disease (ESRD).
Methods: Patients with ESRD who underwent hemodialysis and were treated at our hospital from December 2021 to December 2023 according to the inclusion and exclusion criteria were selected and randomly assigned into two groups: the experimental group (patients received intermittent hemodialysis filtration mode treatment, n = 50) and the control group (patients received conventional maintenance hemodialysis treatment, n = 49). Subsequently, the participant characteristics, the treatment effect, the occurrence of intradialytic hypotension, the safety assessment, blood pressure indicators, and the nutritional status were compared between the two groups.
Prevalence of Metabolic Syndrome and Combinations of Its Components: Findings from the Mexican National Health and Nutrition Survey, 2021.
Metab Syndr Relat Disord
March 2025
Center for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, México.
Metabolic syndrome (MetS) is a clinical construct that conglomerates risk factors interconnected with cardiovascular diseases and type 2 diabetes. More than a thousand million individuals in the world were diagnosed with MetS in 2018. Our objective was to examine the prevalence of MetS and its components among Mexican adults.
View Article and Find Full Text PDFFemtosecond laser-ablative aqueous synthesis of multi-drug antiviral nanoparticles.
Nanomedicine (Lond)
March 2025
Department of Chemistry and The Institute for Laser, Photonics, and Biophotonics, University at Buffalo, The State University of New York, Buffalo, NY, USA.
Background: Nanomedicine offers a number of innovative strategies to address major public health burdens, including complex respiratory illnesses. In this work, we introduce a multi-drug nanoparticle fabricated using femtosecond laser ablation for the treatment of influenza, SARS-CoV-2, and their co-infections.
Methods: The SARS-CoV-2 antiviral, remdesivir; the influenza antiviral, baloxavir marboxil; and the anti-inflammatory, dexamethasone, were co-crystalized and then ablated in aqueous media using a femtosecond pulsed laser and subsequently surface modified with the cationic polymer, chitosan, or poly-d-lysine.
Amino Acid Digestibility of Yellow Mealworm-Based Ingredients using the Precision-Fed Cecectomized Rooster Assay.
J Anim Sci
March 2025
Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Yellow mealworms (Tenebrio molitor) serve as an alternative protein source. Because the amino acid (AA) concentrations, AA digestibility, and protein quality of ingredients may vary depending on their husbandry, harvest and processing procedures, and other factors, each should be evaluated separately. The objective of this study was to measure the AA composition, AA digestibility, and protein quality of yellow mealworm-based ingredients using the precision-fed cecectomized rooster assay.
View Article and Find Full Text PDFBruton tyrosine kinase covalent inhibition shapes the immune microenvironment in chronic lymphocytic leukemia.
Haematologica
March 2025
Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain; Department of Medicine, Universitat Autònoma de Barcelona, Bellaterra.
Continuous treatment with ibrutinib not only exerts tumor control but also enhances T cell function in patients with chronic lymphocytic leukemia (CLL). We conducted longitudinal multi-omics analyses in samples from CLL patients receiving ibrutinib upfront to identify potential adaptive mechanisms to Bruton tyrosine kinase (BTK) inhibition during the first 12 months of continuous therapy. We found that ibrutinib induced a decrease in the expression of exhaustion markers and the proportion of Tregs and Tfh cells normalized to levels observed in healthy donors.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!