Background: Many Indigenous youth and young adults in Canada, the United States, Australia, and New Zealand have reported low vaccine confidence, which has been linked to lower vaccination rates for COVID-19, MMR, HPV, DTaP-IPV-Hib, and pneumococcal conjugate vaccines. Narrative-based health promotion approaches, including those focused on strengthening vaccine confidence, have been used in public health interventions. Scoping reviews have become increasingly valued for their rigorous and reproducible exploration of evidence in public health research. The aim of this scoping review was to understand the extent and types of evidence related to the facilitators, challenges, and benefits of narrative-based health promotion approaches in vaccine confidence interventions within Indigenous populations.
Methods: This review adhered to the Joanna Briggs Institute (JBI) guidelines for scoping reviews using Covidence online software to streamline the review process. Database searches were conducted in MEDLINE, Embase, Web of Science, PsycINFO, and PubMed, as well as Google search to identify both academic and gray literature articles on the role of narratives in promoting vaccine confidence published between January 2000 and April 2024. Charted data were ranked in a numerical summary and analyzed using qualitative content analysis. The review process embraced a two-eyed seeing approach.
Results: The searches identified 306 records. After the screening process, 45 sources (35 peer-reviewed articles, eight gray literature, and two preprint articles) were included in the final review. The key facilitators of narrative-based approaches to promote vaccine confidence were community engagement, tailored and culturally safe interventions, and trusted messengers and sources of information. The challenges discussed in the literature were linked to mistrust of government and healthcare services and to misinformation narratives. The most frequently reported benefits were the development of community-based resources, culturally safe and relevant interventions, building trust and respectful relationships, and improved vaccination rates.
Conclusion: This review confirmed the important contribution of narrative-based health promotion approaches in strengthening vaccine confidence among Indigenous populations. This finding underscores the importance of respecting Indigenous sovereignty and engaging community perspectives to repair trust and improve vaccination rates.
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http://dx.doi.org/10.1186/s12939-025-02424-3 | DOI Listing |
Am J Epidemiol
March 2025
MAP-Centre for Urban Health Solutions, St. Michael's Hospital, Unity Health Toronto, Toronto, ON, Canada.
Knowledge of patterns in COVID-19 deaths by area-level income over time and the mediating role of vaccination in inequality patterns remains limited. We used data from a population-based retrospective cohort of 11,248,572 adults in Ontario, Canada. Cause-specific hazard models were used examine the relationship between income 2016 Census at the dissemination area level) and COVID-19 deaths between March-1-2020 and January-30-2022, stratified by wave.
View Article and Find Full Text PDFJ Natl Cancer Inst
March 2025
Viroclinics-DDL (a Cerba Research company), DDL Diagnostic Laboratory, Rijswijk, The Netherlands.
Background: Following human papillomavirus (HPV) vaccine introduction, declines in the prevalence of HPV vaccine types have been observed in screening cytology, but data from the United States describing HPV type-specific changes in cervical intraepithelial neoplasia (CIN) grades 2-3 and adenocarcinoma in situ (CIN2/CIN3/AIS) are limited.
Methods: A state-wide sample of individuals with cervical biopsies was selected for broad-spectrum HPV genotyping. CIN2/CIN3/AIS incidence and prevalence were calculated for type-specific high-risk HPV (hrHPV) among individuals aged 15-29 years.
BMC Infect Dis
March 2025
U.S. Military HIV Research Program, CIDR, , Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Background: Persons living with HIV (PLWH) were prioritized for SARS-CoV-2 vaccination in sub-Saharan Africa, however, SARS-CoV-2 infection and COVID-19 symptomatology have not been well characterized among PLWH. We described SARS-CoV-2 infection prevalence and symptomatology, and examined factors associated with nasal swab RT-PCR positivity in Kenya, Uganda, Tanzania, and Nigeria.
Methods: The ongoing African Cohort Study (AFRICOS) follows PLWH and people living without HIV (PLWoH) in four African countries.
Vaccine
March 2025
Medical Evidence, Vaccines & Immune Therapies, BioPharmaceuticals Medical, AstraZeneca, Cambridge, UK.
Background: Booster doses of COVID-19 vaccines are required to maintain protection against SARS-CoV-2. However, real-world evidence from South America, needed to inform optimal vaccination strategies, is lacking. Herein, we present the final analysis of REFORCO-Brazil, a large-scale assessment of relative vaccine effectiveness (rVE) of second boosters (vs first boosters) against hospitalization with COVID-19.
View Article and Find Full Text PDFHum Vaccin Immunother
December 2025
Sixth Form Department, Townley Grammar School, Bexleyheath, UK.
We explored adolescent viewpoints on vaccines and hesitancy using an anonymized, validated, self-completed electronic questionnaire amongst state-school Year 12-13 adolescents in London, UK. As the response rate was low (Cohort 1; = 112/486, 23.0%), we repeated the survey with incoming students (cohort 2, = 256/275; 93%).
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