Background: Most nurses with PhDs typically work in academic settings, although some remain in clinical settings. Little is known about the support systems and challenges they encounter in these clinical environments. The objective of this study was to comprehensively investigate and gain valuable insights into the experiences of nursing faculties in clinical settings, focusing specifically on the factors that facilitate or hinder their work and professional development.
Methods: This study used a content analysis method. The participants were selected through purposeful sampling and considered maximum diversity. Data was collected in Tehran between July and September 2023, utilizing a semi-structured interview approach. The analysis process was conducted using the Graneheim and Lundman method, utilizing MAXQDA software version 10.
Results: The study identified 16 nursing PhD faculties, whose experiences were categorized into four categories: personal, nursing faculty, hospital, and professional domains, all nested under the overarching theme of under-acknowledged expertise. Within these categories, key facilitators included enhanced clinical education, professional identity development, and evidence-based practice integration. Barriers included limited clinical expertise, insufficient financial resources, heavy workloads, and social stigma associated with dual academic and clinical roles.
Conclusions: Besides some facilitators, nursing PhD faculties are faced with multifaceted challenges in clinical settings. Addressing identified challenges and leveraging facilitators can promote the professional growth and well-being of nursing faculties, resulting in improved patient care.
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http://dx.doi.org/10.1186/s12912-025-02856-w | DOI Listing |
Biometrics
January 2025
Vanke School of Public Health, Tsinghua University, Beijing, 100084, China.
The segmented model has significant applications in scientific research when the change-point effect exists. In this article, we propose a comprehensive semiparametric framework in segmented models to test the existence and estimate the location of change points in the generalized outcome setting. The proposed framework is based on a semismooth estimating equation for the change-point estimation and an average score-type test for hypothesis testing.
View Article and Find Full Text PDFJAMA Cardiol
March 2025
Department of Cardiovascular Medicine and Section on Geriatrics and Gerontology, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Importance: Excess body fat plays a pivotal role in the pathogenesis of heart failure with preserved ejection fraction (HFpEF). HU6 is a novel, controlled metabolic accelerator that enhances mitochondrial uncoupling resulting in increased metabolism and fat-specific weight loss.
Objective: To assess efficacy and safety of HU6 in reducing body weight, improving peak volume of oxygen consumption (VO2) and body composition among patients with obesity-related HFpEF.
JAMA Cardiol
March 2025
Stanford University School of Medicine, Stanford University, Stanford, California.
Importance: Outcomes in patients with diabetes after fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) using current-generation drug-eluting stents (DES) compared with coronary artery bypass grafting (CABG) are unknown.
Objectives: To investigate the relative treatment effect of PCI vs CABG according to diabetes status with respect to major adverse cardiac and cerebrovascular events (MACCE) at 3 years and to evaluate the impact of the SYNTAX score.
Design, Setting, And Participants: This is a prespecified subgroup analysis of the FAME (Fractional Flow Reserve vs Angiography for Multivessel Evaluation) 3 trial, an investigator-initiated, randomized clinical trial conducted at 48 centers worldwide.
JAMA Psychiatry
March 2025
Center for Neuropsychiatric Schizophrenia Research (CNSR& Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS), Mental Health Centre Glostrup, Copenhagen University Hospital - Mental Health Services CPH, Copenhagen, Denmark.
Importance: Maternal inflammation during pregnancy has been associated with an increased risk of neurodevelopmental disorders (NDDs), such as attention-deficit/hyperactivity disorder (ADHD) and autism, and cognitive deficits in early childhood. However, little is known about the contributions of a wider range of inflammatory proteins to this risk.
Objective: To determine whether maternal inflammatory proteins during pregnancy are associated with the risk of NDDs and executive functions (EF) in middle childhood and to identify protein patterns associated with NDDs and EF.
JAMA Dermatol
March 2025
Service de Dermatologie et Allergologie, Faculté de Médecine, Sorbonne Université, Hôpital Tenon, Assistance Publique-Hôpitaux de Paris, Paris, France.
Importance: VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) is a monogenic disease caused by UBA1 somatic variants in hematopoietic progenitor cells, mostly involving adult men. It is associated with inflammatory-related symptoms, frequently involving the skin and hematological disorders. Recently described myelodysplasia cutis (MDS-cutis) is a cutaneous manifestation of myelodysplasia in which clonal myelodysplastic cells infiltrate the skin.
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