Canine parvoviral enteritis is one of the most common causes of morbidity and mortality in young dogs worldwide. The virus is endemic in the environment and can be infective to unvaccinated or poorly vaccinated dogs. Standard in-patient therapies include use of antiemetics, intravenous fluids, antibiotics and provision of enteral nutrition. The use of antiviral drugs, immunomodulators and monoclonal antibody therapy are newer possibilities that may potentially improve outcome. Outpatient therapy also remains a viable possibility for treatment if financial constraints exist.
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http://dx.doi.org/10.1016/j.cvsm.2025.01.002 | DOI Listing |
J Vet Intern Med
March 2025
Department of Virology, Faculty of Veterinary Medicine, Atatürk University, Erzurum, Turkey.
Background: The trace elements copper (Cu), zinc (Zn), and selenium (Se) have been the focus of research into their potential roles in the prognosis of gastrointestinal disorders in humans.
Objective: Evaluation of the predictive potential serum concentrations of Cu, Zn, Cu/Zn, Se, and cobalamin as possible prognostic indicators in dogs with parvoviral enteritis (CPV).
Animals: Client-owned dogs diagnosed with CPV (n = 20) and healthy controls (n = 10).
Vet Clin North Am Small Anim Pract
March 2025
Cornell University, 880 Canal Street, Stamford, CT 06902, USA; Emergency and Critical Care, Cornell University Hospital for Animals, Ithaca, NY, USA. Electronic address:
Canine parvoviral enteritis is one of the most common causes of morbidity and mortality in young dogs worldwide. The virus is endemic in the environment and can be infective to unvaccinated or poorly vaccinated dogs. Standard in-patient therapies include use of antiemetics, intravenous fluids, antibiotics and provision of enteral nutrition.
View Article and Find Full Text PDFJ Virol
January 2025
Guangdong Technological Engineering Research Center for Pets, College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong, China.
Unlabelled: Canine parvovirus type 2 (CPV-2) is a member of the Parvoviridae family, characterized by its small, non-enveloped virions containing a linear single-stranded DNA genome of approximately 5 kb. Parvoviruses entirely reliant on the host cell's division machinery for replication. In this study, we demonstrate that CPV-2 infection triggers the host translation shutoff, a process in which the nonstructural protein 1 (NS1) plays a pivotal role.
View Article and Find Full Text PDFVet Med (Praha)
October 2024
Department of Internal Medicine, Faculty of Veterinary Medicine, Bursa Uludag University, Bursa, Turkey.
Am J Vet Res
January 2025
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
Objective: To determine the association between ionized calcium (iCa) and/or total magnesium (tMg) and the development of sepsis and to investigate whether iCa or tMg is associated with mortality in puppies with canine parvoviral enteritis (CPE).
Methods: 64 client-owned puppies with CPE were enrolled in this prospective cohort study. Serum iCa and tMg were measured daily from admission until death or discharge.
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