Introduction: Myopericytoma is an uncommon benign neoplasm composed of myoid-appearing perivascular cells. It had been reported in various soft tissues, but only few case reports were found reported in liver.
Case Presentation: We reported a case of myopericytoma in a 43-year-old female with a history of a left adnexal cyst and foul-smelling per vaginal discharge with no significant findings in per abdominal examination. Imaging studies initially suggested the possibility of hemangioma in ultrasonography and further CT scan was advised which gave the possibility of focal nodular hyperplasia.
Clinical Discussion: Right hemihepatectomy was performed and histopathological examination revealed a well-circumscribed mass consistent with myopericytoma, supported by positive immunohistochemical staining for SMA and H caldesmon, and negativity for Desmin, DOG-1, and ALK.
Conclusion: This case contributes to the limited literature on hepatic myopericytoma and emphasizes the importance of considering this entity in the differential diagnosis of liver lesion.
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http://dx.doi.org/10.1016/j.ijscr.2025.111110 | DOI Listing |
Int J Surg Case Rep
March 2025
Department of Pathology, Tribhuvan University Teaching Hospital (TUTH), Maharajgunj, Kathmandu, Bagmati Province, Nepal.
Introduction: Myopericytoma is an uncommon benign neoplasm composed of myoid-appearing perivascular cells. It had been reported in various soft tissues, but only few case reports were found reported in liver.
Case Presentation: We reported a case of myopericytoma in a 43-year-old female with a history of a left adnexal cyst and foul-smelling per vaginal discharge with no significant findings in per abdominal examination.
Mod Pathol
January 2025
Department of Pathology, Boston Children's Hospital, Boston, Massachusetts. Electronic address:
Soft tissue tumors with smooth muscle differentiation are rare in pediatric patients. Despite often showing morphologic features sufficient for classification as "leiomyosarcoma" in adults (eg, high cellularity and mitotic activity), clinical follow-up has shown only indolent behavior. The pathological features of recently reported SRF-rearranged "cellular myofibromas/myopericytomas," typically occurring in children, overlap with those of true smooth muscle tumors.
View Article and Find Full Text PDFSkeletal Radiol
December 2024
Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10021, USA.
Myopericytoma is a rare benign smooth-muscle cell neoplasm of the subcutaneous soft tissues that is primarily found in young adults with a male predominance. We present the clinical, radiologic, and histopathologic features of a longstanding myopericytoma of the hand. We emphasize the features that help the radiologist and pathologist to accurately characterize this entity.
View Article and Find Full Text PDFAm J Gastroenterol
November 2024
Oregon Health & Science University, Portland, Oregon, USA.
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