Objective: This study aims to evaluate the enhancement of speech functionality in adult patients with cleft palate through acoustic analysis, assessing pronunciation level improvements before and after palatopharyngoplasty and speech treatment. The findings aim to provide an objective assessment of the treatment efficacy for older patients with cleft palate.
Participants And Intervention: The study involved acoustic comparisons encompassing vowel formants, voice onset time (VOT) of consonant syllables, syllable duration, and voice characteristic analysis. Speech functionality in each adult cleft palate patient was evaluated thrice: before palatopharyngoplasty, after palatopharyngoplasty, and following speech therapy, using a self-comparative analysis method to discern phonological differences.
Results: No significant alteration in vowel formants was observed in adult cleft palate patients pre-palatopharyngoplasty and post-palatopharyngoplasty. Post-speech treatment, the F2 and F3 values for the anterior high vowel /i/ significantly improved, aligning closely with those of the normal adult group. Similarly, while consonant parameters (VOT value and syllable duration) remained unchanged post-surgery, both metrics showed significant improvement after speech therapy. Except for the prolonged syllable duration of /s/ compared with normal adults, other indicators were not significantly different. Voice parameter analysis revealed no significant change post-operation; however, both HNR and CPPS values post-speech treatment notably increased, matching those of normal adults.
Conclusion: Surgical intervention addresses the physical closure of the cleft palate and reconstructs the resonator's structure. Conversely, consonant improvement predominantly occurs through targeted speech therapy aimed at rectifying pronunciation habits and tutoring patients on the effective utilization of repaired articulatory organs. The combined intervention of cleft palate surgery and speech therapy plays a complementary role in speech restoration for cleft palate patients.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/SCS.0000000000010495 | DOI Listing |
J Stomatol Oral Maxillofac Surg
March 2025
BDS, MSc, Ph.D, associate professor, Department of Clinical Oral Health Sciences, College of Dental Medicine, QU Health, Qatar University, Doha, Qatar. Electronic address:
Introduction: This study aimed to assess the available evidence regarding the skeletal, dentoalveolar and soft tissue effects of different maxillary expansion appliances in cleft lip/palate patients.
Methods: We assessed the effects of different maxillary expansion appliances on skeletal structure and dentoalveolar and soft tissue in cleft lip/palate patients. We searched the PubMed, Science Direct, Web of Science, Cochrane, and LILACS databases through September 2024; that investigation was augmented by a manual search.
iScience
March 2025
College of Life and Environmental Sciences, Zhejiang Key Laboratory of Organ Development and Regeneration, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.
The specific roles of nonsense-mediated mRNA decay (NMD), a translation-dependent RNA quality control mechanism that degrades mRNAs containing premature termination codons (PTCs), in mammalian craniofacial development have remained unclear. Here, we show that knockout of the essential NMD factor in mouse craniofacial neural crest cells leads to hypoplastic mandibles, subsequently inducing tongue mispositioning and cleft palate formation. Furthermore, loss triggers massive cell apoptosis and disrupts cell differentiation, accompanied by widespread alterations in alternative splicing and a surge in PTC-containing mRNA levels.
View Article and Find Full Text PDFJ World Fed Orthod
March 2025
Institute for Research in Dental Sciences, School of Dentistry, Universidad de Chile, Santiago, Chile. Electronic address:
Background: DNA methyltransferase 1 (DNMT1) is responsible for epigenetic remodeling of the genome during spermatogenesis and maintenance of DNA methylation. The current study aimed to assess the possible association between paternal polymorphic variants of the gene encoding DNMT1 enzyme and the risk of nonsyndromic cleft lip with or without cleft palate (NSCL/P) expression in offspring.
Methods: Nine DNMT1 polymorphic single nucleotide polymorphism (SNP) variants were analyzed in 101 fathers of NSCL/P Chilean cases and 187 fathers of controls.
Front Pediatr
February 2025
Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Background: Pierre Robin sequence (PRS) is characterized by micrognathia, glossoptosis, and upper airway obstruction. This study aimed to compare the dentoskeletal characteristics of children diagnosed with non-syndromic PRS and those with cleft palate.
Methods: This study was conducted on the non-syndromic PRS patients in the database of our hospital.
Indian J Otolaryngol Head Neck Surg
January 2025
JIIU's Indian Institute of Medical Science and Research, Warudi, Badnapur, Maharashtra India.
In this case we report rare clinical entity of Millers syndrome in a small child of 6 years. It is basically an autosomal recessive condition characterized by anomalies of face and limbs such as malar hypoplasia, micrognathia, cleft lip and palate, restricted airway, bones and joints malformations [1, 2]. In this child apart from all these features we came across bleeding nasal masses attached to the inferior tubinates, which were causing complete nasal obstruction.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!