Motor signs are critical features of psychosis that remain underutilized in clinical practice. These signs, including social motor behaviors, mechanistically relevant motor signs, and other motor abnormalities, have demonstrated potential as biomarkers for early detection and intervention. However, their application in clinical settings remains limited due to challenges such as cost, accessibility, and integration into clinical workflows. Recent advancements in related research fields, such as Human Movement Sciences and Affective Computing, offer promising solutions, enabling scalable and precise measurement of patients motor signs. In this editorial, we explore the spectrum of motor signs and highlight the evolving role of motor assessments in psychosis research. By examining traditional assessment methods alongside alternative and innovative tools, we underscore the potential of leveraging technology and methodology to bridge the gap between research and clinical application, ultimately advancing personalized care and improving outcomes.
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http://dx.doi.org/10.1093/schbul/sbaf010 | DOI Listing |
Neurology
April 2025
Brain Health and Wellness Research Program, St. Michael's Hospital, Unity Health Toronto, Ontario, Canada.
Background And Objectives: Medical clearance for return to play (RTP) after sports-related concussion is based on clinical assessment. It is unknown whether brain physiology has entirely returned to preinjury baseline at the time of clearance. In this longitudinal study, we assessed whether concussed individuals show functional and structural MRI brain changes relative to preinjury levels that persist beyond medical clearance.
View Article and Find Full Text PDFJ Am Acad Orthop Surg Glob Res Rev
March 2025
From the Department of Orthopaedic Surgery, Boston Medical Center Pl, Boston, MA.
Compartment syndrome is an orthopaedic emergency with moderate-to-severe sequela (pain, muscle contracture, nerve damage, infection, rhabdomyolysis, renal failure, etc.) if inadequately treated and can be difficult to diagnose in a timely fashion. Further complicating timely diagnosis are atypical presentations resulting in compartment syndrome.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
March 2025
Padova Neuroscience Center, University of Padova, Padova 35131, Italy.
Resting brain activity, in the absence of explicit tasks, appears as distributed spatiotemporal patterns that reflect structural connectivity and correlate with behavioral traits. However, its role in shaping behavior remains unclear. Recent evidence shows that resting-state spatial patterns not only align with task-evoked topographies but also encode distinct visual (e.
View Article and Find Full Text PDFMed Trop Sante Int
December 2024
Service de neurologie, Centre hospitalier universitaire (CHU) de Cocody, Université Félix Houphouët Boigny, UFR des sciences médicales d'Abidjan, Cote d'Ivoire.
Introduction: Thyrotoxic hypokalemic periodic paralysis (THPP) is a sporadic form of hypokalemic periodic paralysis (HPP). It is a diagnostic and therapeutic emergency rarely described in the black population. We report a case in a black subject from Côte d'Ivoire.
View Article and Find Full Text PDFCureus
February 2025
Emergency Medicine, Duke Lifepoint Conemaugh Memorial Medical Center, Johnstown, USA.
Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy or "broken heart syndrome," is a transient form of myocardial dysfunction often triggered by emotional or physical stress. While typically associated with emotional distress and possible physical stress, TTC has rarely been reported in the context of physical trauma, including blunt chest injuries. This case report describes a novel instance of TTC in an 84-year-old woman who developed the condition following a motor vehicle accident, resulting in blunt chest trauma.
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