Tantalum (Ta) metal has emerged as a prominent material within the realm of bone tissue engineering, owing to its favorable biocompatibility, commendable mechanical attributes, and notable biological properties such as osteoconductivity, osteoinductivity, and angiogenic potential. However, as clinical applications have expanded, Ta implants have unveiled a spectrum of limitations. Consequently, porous tantalum (PTa) has garnered escalating interest, attributable to its unique microstructural attributes, tunable mechanical characteristics, and inherent biocompatibility. Various methodologies have been proposed to modify the surface of PTa, with the aim of accelerating and enhancing osseous integration while fostering more robust osseointegration. Strategic surface modifications have the potential to augment the inherent advantages of PTa, thereby offering diverse avenues for exploration within the realm of surface effects on PTa. This review elucidates the ongoing research endeavors concerning diverse biomaterial coatings applied to PTa surfaces in the context of bone tissue engineering.
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http://dx.doi.org/10.1007/s10856-025-06871-w | DOI Listing |
Br Poult Sci
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The National Institute of Poultry Husbandry, Harper Adams University, Newport, UK.
1. This study examined feeding practices that could affect the expression of intestinal calcium transporter gene, tibial mass, eggshell quality and production performance in 25-week-old Hy-Line Brown Laying Hens.2.
View Article and Find Full Text PDFForaminal and extraforaminal lumbar disc herniations are common sources of pain and disability. Classic surgical treatments, such as open approach through Witsel technique, often involve resection of the superior articular process to decompress the foraminal space. Unilateral biportal endoscopy (UBE) has emerged as a minimally invasive alternative, providing enhanced visualization and precision while minimizing soft tissue damage.
View Article and Find Full Text PDFCancer Rep (Hoboken)
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UOC Haematology, ASL Viterbo-Santa Rosa Hospital, Viterbo, Italy.
Background: Multiple myeloma (MM) is more often characterized by clonal plasma cell proliferation restricted to the bone marrow. However, a small percentage of patients with MM develop extramedullary disease (EMD): this type of localization is found in 1.7%-4.
View Article and Find Full Text PDFEndokrynol Pol
March 2025
Department of Endocrinology and Metabolism, Changzhi Medical College Affiliated Heji Hospital, Changzhi, China.
Bone mineral density is the primary basis for the diagnosis of osteoporosis. Bone mineral density measurement methods include dual-energy X-ray (DXA) and quantitative computed tomography (QCT). Based on traditional bone density detection equipment, the newly developed imaging detection technology can further detect the microstructures and geometric features of bones, providing important reference for exploring the pathophysiological changes, sensitive clinical diagnosis, and disease monitoring of osteoporosis.
View Article and Find Full Text PDFOrthop Surg
March 2025
Department of Orthopaedic Surgery and Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Recent literature has increasingly demonstrated the significant function of autonomic nerves in regulating physiological and pathological changes associated with the skeletal system. Extensive studies have been conducted to understand the contribution of the autonomic nervous system (ANS) to skeletal metabolic homeostasis and resistance to aseptic inflammation, specifically from the viewpoint of skeletal neurobiology. There have been plenty of studies on how the sympathetic nervous system (SNS) and parasympathetic nervous system (PNS), the two main branches of the ANS, regulate bone remodeling, which is the process of bone formation and resorption.
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