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| http://dx.doi.org/10.1007/s00415-024-12808-0 | DOI Listing |
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Inadequate sleep increases stroke risk: evidence from a comprehensive meta-analysis of incidence and mortality.
Geroscience
March 2025
Dept. Of Bioinformatics, Semmelweis University, 1094, Budapest, Hungary.
The link between abnormal sleep duration and stroke outcomes remains contentious. This meta-analysis quantifies how both short and long sleep durations impact stroke incidence and mortality. A comprehensive search was conducted in PubMed, Web of Science, Cochrane Library, Embase, and Google Scholar up to November 1, 2024, to identify cohort studies evaluating sleep duration and stroke outcomes.
View Article and Find Full Text PDFCould adaptive deep brain stimulation treat freezing of gait in Parkinson's disease?
J Neurol
March 2025
Centre for Neurology, Department of Neurodegenerative Diseases, and Hertie Institute for Clinical Brain Research, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.
Next-generation neurostimulators capable of running closed-loop adaptive deep brain stimulation (aDBS) are about to enter the clinical landscape for the treatment of Parkinson's disease. Already promising results using aDBS have been achieved for symptoms such as bradykinesia, rigidity and motor fluctuations. However, the heterogeneity of freezing of gait (FoG) with its wide range of clinical presentations and its exacerbation with cognitive and emotional load make it more difficult to predict and treat.
View Article and Find Full Text PDFSarcopenia and frailty in critical illness.
Curr Opin Clin Nutr Metab Care
March 2025
Division of Human Nutrition and Health, Wageningen University & Research, Wageningen.
Purpose Of Review: Sarcopenia and frailty are common conditions, associated with worse clinical outcomes during critical illness. Recent studies on sarcopenia and frailty in ICU patients are presented in this review, aiming to identify accurate diagnostic tools, investigate the effects on clinical and functional outcomes, and propose possible effective interventions.
Recent Findings: The recent change of the sarcopenia definition underlines the importance of muscle strength over mass, this is however challenging to assess in ICU patients.
Gut Microbiota Modulation of Dementia Related Complications.
Aging Dis
March 2025
First Clinical Medical College, Heilongjiang University of Chinese Medicine, Harbin 150040, China.
Recent advances in microbial pathogen research have highlighted the potential of gut microbe-based microbial medicine. One of the most extensively studied biological pathways is the gut-brain axis, which has been shown to reverse neurological disorders. Evidence from animal-based studies of dysbiosis suggest complex behavioral changes, such as alterations in sociability and anxiety, can be modulated through gut microbiota.
View Article and Find Full Text PDFA meta-analysis of the impact of technology related factors on students' academic performance.
Front Psychol
February 2025
Physical Education and Sports Department, Faculty of Sport Sciences, Hitit University, Çorum, Türkiye.
Introduction: The relationship between students' smartphone addiction, social media use, video games play, and their academic performance has been widely studied, yet the existing literature presents inconsistent findings. This meta-analysis synthesizes current research to provide a comprehensive examination of the impact of these technologies on academic achievement.
Methods: A total of 63 studies (yielding 64 effect sizes) were included, encompassing a sample of 124,166 students from 28 countries.
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