The practice of fluoroscopy during pediatric endoscopic kidney stone procedures requires attention because of radiation concerns that demand new treatment methods. This study aimed to present the multicentric results of single guide wire flexible ureterorenoscopy (URS) and retrograde intrarenal surgery (RIRS) procedures without fluoroscopy and an ureteral access sheath (UAS) in treating kidney stones in pediatric patients. Moreover, we aim to evaluate the efficacy and safety of this procedure to ascertain the feasibility of this radiation-free therapeutic intervention for treating kidney stones in children. A retrospective analysis was done on the data of 105 pediatric patients who underwent retrograde intrarenal surgery (RIRS) treatment in two tertiary healthcare centers without fluoroscopy and UAS between May 2014 and May 2024. Of these 105 patients evaluated, 74 (70.5%) were male and 31 (29.5%) were female. The patients had a mean age of 71 ± 4 (ranging from 6 to 204) months. The mean size of stones was 9.3 ± 5 (ranging from 6 to 20) mm, and the average operation time was 51 (ranging from 31 to 98) minutes. Additionally, in 24 (22.8%) patients, the flexible URS could not proceed through the ureteral orifice. Thus, a double J stent was inserted, and the surgical procedure was repeated one month later without any complications. However, 2 (1.9%) of the patients experienced postoperative fever, and 6 (5.7%) patients had minor complications related to haematuria. Stone-free status was observed in 87 out of 105 patients (82.9%). Despite using a single guide wire without fluoroscopy and UAS in treating kidney stones in pediatric patients, the RIRS procedure is technically effective and safe. It may be considered a viable non-surgical procedure that is effective in safeguarding pediatric patients from the harmful effects of radiation, rendering it a promising alternative for pediatric urolithiasis management.
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http://dx.doi.org/10.1007/s00240-025-01719-y | DOI Listing |
J Clin Rheumatol
March 2025
From the Department of Pediatric Rheumatology, Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School.
Objectives: Our study aimed to identify potential predictors for additional systemic involvement in patients with noninfectious uveitis, specifically focusing on their demographic, etiological, clinical, and laboratory data features from the pediatric rheumatology perspective.
Methods: Patients with noninfectious uveitis before the age of 18 years and followed up for at least 3 months in 2 tertiary centers of pediatric rheumatology and ophthalmology departments were included in the study. Demographics, etiology, clinical features, laboratory data, and treatments administered were evaluated and compared based on the etiology (idiopathic and systemic disease-related uveitis [SD-U]) and the use of biologic disease-modifying antirheumatic drugs.
Pediatr Infect Dis J
March 2025
Divisions of Pediatric Emergency Medicine and Pediatric Infectious Diseases, Baylor College of Medicine, Houston, Texas.
Background: Infection is a leading cause of death after pediatric heart transplants (PHTs). Understanding of common pathogens is needed to guide testing strategies and empiric antibiotic use.
Methods: We conducted a 3-center retrospective study of PHT recipients ≤18 years old presenting to cardiology clinics or emergency departments (EDs) from 2010 to 2018 for evaluation of suspected infections within 2 years of transplant.
Pediatr Infect Dis J
March 2025
National Reference Laboratory for Plague, Tularemia and Q Fever.
Mediterranean spotted fever has recently been reported in Iran, yet it continues to be overlooked by healthcare professionals in the country. This case report details a 19-month-old child who presented with fever, edema and skin rashes and was initially misdiagnosed. Subsequent testing revealed a Mediterranean spotted fever infection through IgG seroconversion.
View Article and Find Full Text PDFPediatr Infect Dis J
March 2025
Infectious Diseases Unit, Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
Pediatr Infect Dis J
March 2025
From the Department of Pediatrics.
Background: Critically ill children are at risk for subtherapeutic antibiotic concentrations. The frequency of target attainment and risk factors for subtherapeutic concentrations of cefepime in children have not been extensively studied.
Methods: We performed an observational study in critically ill children receiving a new prescription of standard dosing of cefepime for suspected sepsis (≥2 systemic inflammatory response syndrome criteria within 48 hours of cefepime start).
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