The increasing morbidity and mortality of dementia places a significant burden on society in economic, social and health terms. In addition to the therapy of partially detectable etiologies, diet can also play a major role in reducing the risk of dementia. The most commonly studied dietary patterns in relation to cognitive decline are the Mediterranean diet, the DASH (Dietary Approaches to Stop Hypertension) diet for the prevention of hypertension, and the MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet, which has emerged as a new approach in the last decade, combining elements of the Mediterranean and DASH diets, but there is also considerable research on the ketogenic diet and intermittent fasting. This study aims to summarise all dietary factors that may play a role in the prevention and development of cognitive decline.
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http://dx.doi.org/10.18071/isz.78.0005 | DOI Listing |
JAMA Netw Open
March 2025
Department of Psychiatry, University of Oxford, Oxford, United Kingdom.
Importance: Epidemiological studies suggest that lifestyle factors are associated with risk of dementia. However, few studies have examined the association of diet and waist to hip ratio (WHR) with hippocampus connectivity and cognitive health.
Objective: To ascertain how longitudinal changes in diet quality and WHR during midlife are associated with hippocampal connectivity and cognitive function in later life.
Microb Biotechnol
March 2025
Nova Institute for Health, Baltimore, Maryland, USA.
Advances in neuromicrobiology and related omics technologies have reinforced the idea that unseen microbes play critical roles in human cognition and behaviour. Included in this research is evidence indicating that gut microbes, through direct and indirect pathways, can influence aggression, anger, irritability and antisocial behaviour. Moreover, gut microbes can manufacture chemicals that are known to compromise cognition.
View Article and Find Full Text PDFInt J Cancer
March 2025
Center for Epigenetics & Disease Prevention, Texas A&M HEALTH, and Department of Translational Medical Sciences, Texas A&M University Naresh K. Vashisht College of Medicine, Houston, Texas, USA.
A previously reported clinical trial in familial adenomatous polyposis (FAP) patients treated with erlotinib plus sulindac (ERL + SUL) highlighted immune response/interferon-γ signaling as a key pathway. In this study, we combine intermittent low-dose ERL ± SUL treatment in the polyposis in rat colon (Pirc) model with mechanistic studies on tumor-associated immune modulation. At clinically relevant doses, short-term (16 weeks) and long-term (46 weeks) ERL ± SUL administration results in near-complete tumor suppression in Pirc colon and duodenum (p < 0.
View Article and Find Full Text PDFWomens Health (Lond)
March 2025
Center for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Background: Retention of weight postpartum increases risk for long-term morbidity, including cardiometabolic disease. Although retained weight postpartum is a complex problem, interventions generally address individual diet and activity behaviors.
Objectives: We investigated the impact of social-network factors on postpartum health behaviors and weight.
Anim Biotechnol
December 2025
Faculty of Science, Dookie College, The University of Melbourne, Melbourne, Australia.
This study aimed to 1) Establish relationships between feed conversion efficiency (FCE; live weight gain/intake) and several biomarkers in pigs using blood and hair samples, and 2) Investigate the relative FCE performance of pigs from maternal vs. terminal genetic lines fed high vs. low energy diets.
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