Background And Purpose: Despite being recognised for a long time as a non-motor characteristic of Parkinson's disease (PD), pain is still a symptom that is underdiagnosed and undertreated. This study aimed to assess the relationship between PD patients' pain and sleep disturbances, depression, cognitive functions, fatigue and quality of life.
Methods: A total of 100 patients with primary PD were recruited for this study. Their demographic and clinical features, including age, gender distribution, educational level, smoking, lateralization and duration of PD, and comorbid diseases were recorded. The patients were divided into two groups: patients with and without pain. The scores on the Unified Parkinson's Disease Rating Scale (UPDRS), Hoehn and Yahr Scale, Mini-Mental State Examination, Parkinson's Disease Questionnaire-39 (PDQ-39), Fatigue Severity Scale, Beck Depression and Anxiety Inventories, and Epworth Sleepiness Scale were compared between the two groups.
Results: Statistical analyses regarding questionnaires revealed higher scores in various domains for PD patients with pain, although significance was not found in all measures (p > 0.05). However, PDQ-39 test scores were significantly higher in PD patients with pain compared to those without pain (p = 0.036). Patients with pain presented significantly higher scores than those without pain for all domains of the UPDRS and Hoehn-Yahr Scale (p < 0.05). In order of frequency, musculoskeletal pain, radicular pain, parkinsonian pain, headache, neuropathic pain, and inflammatory pain were detected.
Conclusion: Our findings show that pain was prevalent in more than half of the participants, with musculoskeletal pain being the most common type. Additionally, experiencing multiple types of pain concurrently may highlight the complexity of pain presentation in this population, suggesting that pain in PD is frequent, complex, and related to impairment of quality of life of the patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.18071/isz.78.0056 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Background: Neuroendocrine carcinomas (NECs) are rare tumors from hormone-secreting neuroendocrine cells, often within the gastrointestinal tract. The authors report what is, to their best knowledge, the first case of a small intestine NEC metastasizing to the temporomandibular joint (TMJ).
Case Description: A 60-year-old man came to the oral medicine, oncology, and orofacial pain clinic with a chief concern of left-sided jaw pain.
The Effects of Korean Hand Acupressure on Postoperative Pain, Nausea, Vomiting, and Retching After Thyroidectomy.
J Perianesth Nurs
March 2025
Department of General Surgery, Istanbul Prof. Dr. Cemil Taşcıoğlu City Hospital, Istanbul, Turkey.
Purpose: There are studies examining the effect of Chinese acupressure on postoperative nausea, vomiting, and retching, but there is no study examining the effect of Korean hand acupressure. The study was conducted to determine the effect of Korean hand acupressure applied after thyroidectomy on the number and severity of postoperative pain, nausea, vomiting, and retching.
Design: An experimental study with a post-test control group design involving randomized groups.
Diagnostic and Therapeutic Potential of Photo-Responsive Nanomaterials in Osteoarthritis.
Aging Dis
March 2025
Medical School of Chinese PLA, Beijing, China.
Osteoarthritis (OA) is the most common musculoskeletal disease globally and is the main reason for the chronic pain and disability in people over sixty-five worldwide. Degradation of the articular cartilage, synovial inflammation and osteophyte formation are widely acknowledged as the primary pathological manifestations of OA. OA affects more than 300 million people all over the world, bringing extremely large socioeconomic burden.
View Article and Find Full Text PDFTrifluoroacetic Acid Induced a Cyclophilin D-Dependent Cognitive Impairment in Mice.
Aging Dis
February 2025
Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
Studies have linked inhalation anesthesia and surgery to increased cognitive impairment, particularly in the elderly. Our previous research showed that isoflurane, but not desflurane, affected cognitive function in mice by modulating cyclophilin D (CypD), a key regulator of the mitochondrial permeability transition pore (mPTP) and mitochondrial function. Both anesthetics metabolize into trifluoroacetic acid (TFA), which is associated with cognitive deficits.
View Article and Find Full Text PDFEffectiveness of ERAS program on postoperative recovery after gastric cancer surgery: a randomized clinical trial.
Int J Surg
March 2025
Department of Surgery and Cancer Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Background: Previous studies have reported the effectiveness of the "enhanced recovery after surgery" program in patients who underwent gastric cancer surgery, mostly based on the 2014 gastrectomy guidelines. Therefore, based on subsequent advancements in perioperative management, this randomized, controlled, open-label, single-center study aimed to assess the impact of a recent evidence-based multimodal enhanced recovery after surgery program on the quality of early recovery after gastric cancer surgery.
Materials And Methods: This study included adult patients scheduled to undergo elective laparoscopic or robotic distal gastrectomy for gastric cancer.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!