Purpose: To determine, using multivariate regression, whether patient-reported outcomes are associated with surgical timing to account for differences between groups.
Methods: Patients who underwent acromioclavicular (AC) joint surgery from 2010 to 2019 were included if they underwent primary AC joint surgery for a Rockwood grade III-V AC joint separation. Chart review was conducted to determine time from injury to surgery, Rockwood injury grade, and surgical technique. Postoperative complications, revisions, American Shoulder and Elbow Surgeons (ASES) score, Single Assessment Numeric Evaluation (SANE) scores, and radiographic outcomes were collected. Radiographic outcomes were determined by measuring coracoclavicular (CC) distance on preoperative, immediate postoperative, and all follow-up anterior-posterior views of the operative shoulder. Multivariate regressions were conducted with postoperative ASES, SANE, and CC distance as the outcomes of interest.
Results: Overall, 221 patients (104 early, 117 delayed) with an average age of 40 ± 15 years were included in this study. Significant differences in patient age, body mass index, injury grade, surgical technique used, and preoperative CC distance were observed between groups (all < .05). After we controlled for confounding variables such as age, sex, body mass index, injury grade, and surgical technique, multivariate regression found that time from injury to surgery was not related to postoperative ASES score (R = 0.137, = .563) or postoperative SANE score (R = 0.087, = .441). Female patients had lower ASES scores than male patients (estimate: -8.25, 95% confidence interval -15.99 to -0.050, = .039); however, no other significant relationships were identified from multivariate regression.
Conclusions: The timing of AC joint surgery did not affect functional outcomes in patients with AC joint separation.
Level Of Evidence: Level III, retrospective cohort study.
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http://dx.doi.org/10.1016/j.asmr.2024.101017 | DOI Listing |
Cells
February 2025
College of Veterinary Medicine/Bio-Medical Center, Huazhong Agricultural University, Wuhan 430070, China.
Osteoarthritis (OA) is one of the most common degenerative diseases in dogs and humans, which can lead to articular cartilage deterioration, chronic pain, and decreased quality of life. The anti-inflammatory, anti-fibrotic, analgesic, and cartilage regeneration properties of mesenchymal stem cell (MSC) therapy provide a new direction for the treatment development of OA in the future. Currently, MSC therapy lacks confirmed ideal sources, dosages, formulations, and specific characteristics.
View Article and Find Full Text PDFPurpose: Total knee arthroplasty (TKA) in patients who underwent previous knee surgeries can be a challenging procedure both technically and for the complication rate. Conversion TKA is affected by a higher risk of infection compared to primary TKA. The aims of this meta-analysis are i) to compare the infectious risk among patients undergoing TKA after a prior hardware implantation, evaluating removal vs maintenance of the hardware, and ii) within the removal group, to compare staged vs concurrent procedure.
View Article and Find Full Text PDFPurpose: No literature consensus was found about the best treatment of acute Rockwood type III acromioclavicular joint (ACJ) dislocation. In particular, the advantages and disadvantages between conservative treatment and surgery are not sufficiently quantified in the current literature.
Methods: A systematic literature search was conducted using PubMed, Web of Science and Embase in March 2024.
Clin Pediatr (Phila)
March 2025
Department of Pediatrics, The Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, China.
Objective: This study was aimed to analyze 10 pediatric cases of pigmented villonodular synovitis (PVNS) of the knee to elucidate their clinical features, diagnosis, treatments, and prognosis for providing reference regarding its clinical management in children.
Methods: A retrospective analysis was made pertaining to the clinical manifestations, magnetic resonance imaging (MRI) findings, pathology, immunohistochemical results, treatment methods, and follow-up outcomes of 10 pediatric PVNS patients of the knee treated from January 2022 to January 2024 at our hospital. They were compared and analyzed with existing literature.
The diagnosis, risk factors, treatment algorithms, and long-term sequelae of superficial and deep, implant-related infections in transdermal, bone-anchored osseointegration are not well-defined. In contrast to the robust experience diagnosing and managing periprosthetic joint infections in total joint arthroplasty, osseointegration surgery has only recently been adopted at a small number of osseointegration centers in the United States, contributing to the lack of long-term outcomes. Through the pooled experience from these osseointegration centers, we present a consensus statement on the perioperative management, incidence, treatment, and diagnostic workup for infectious complications following transdermal, bone-anchored osseointegration.
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