Purpose: To determine the most effective number and location of fixation points for remplissage of Hill-Sachs lesions (HSL) in a cadaveric model of anterior shoulder instability.
Methods: Eleven fresh-frozen cadaveric shoulder specimens were tested. A robot device tested resistance to anterior translation of the humeral head. Eleven shoulder conditions were tested: (1) intact, (2) 15% HSL, (3) 15% HSL with 1 central, (4) 15% HSL with 2 central, (5) 15% HSL with 1 medial, (6) 15% HSL with 2 medial, (7) 30% HSL, (8) 30% HSL with 1 central, (9) 30% HSL with 2 central, (10) 30% HSL with 1 medial, and (11) 30% HSL with 2 medial.
Results: All remplissage techniques tested restored peak resistance to at least equal that of the intact shoulder condition. In the small Hill-Sachs condition, the mean peak resistance for 1 central, 2 central, 1 medial, and 2 medial fixation was 41.5, 52.3, 45.1, and 54.8, respectively. In the large Hill-Sachs condition, the mean peak resistance was 41.7, 59.9, 42.6, and 64.43, respectively. Two fixation points provided more resistance than one in both the medial ( < .01) and central ( < .01) locations. When comparing fixation location, however, there was not a significant difference between 1 central and 1 medial ( > .05) or 2 central to 2 medial ( > .05) in either the large or small HSL.
Conclusions: All remplissage techniques were able to successfully restore mean peak resistance to anterior translation to the native condition in this cadaveric model. There was not a difference in resistance force between medial wall and central placement for either the single- or double-fixation configurations.
Clinical Relevance: This study suggests that one anchor placed either medially or centrally will restore native stability in remplissage for anterior shoulder instability.
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http://dx.doi.org/10.1016/j.asmr.2024.101003 | DOI Listing |
3 Biotech
April 2025
Department of Hospitality Management, College of Agriculture and Health, Tunghai University, Taichung, 407224 Taiwan.
Obesity is linked to cardiovascular disease, cerebrovascular disease, diabetes, and dyslipidemia, lowering quality of life, work productivity, and healthcare expenditures. The aim of this present study is to investigate the mechanism of potato protein (PP) post-treatment in regulating lipogenesis and lipolysis in 3T3-L1 adipocytes. 9% PP hydrolysed for 2 h (PPH902) shows high yield and better activity; thus, PPH902 was used in all other experiments.
View Article and Find Full Text PDFClin Transl Med
March 2025
UCL Division of Surgery and Interventional Sciences, London, UK.
Med Microbiol Immunol
March 2025
Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmaceutical Sciences, Hainan University, Haikou, 570228, China.
Burkholderia cenocepacia, an opportunistic pathogen, poses a significant threat to human health, necessitating the discovery of effective quorum sensing inhibitors (QSIs). In this study, the quorum sensing inhibitory effects of deferiprone (DFP) on the B. cenocepacia 162,638 were validated.
View Article and Find Full Text PDFArthrosc Sports Med Rehabil
February 2025
Department of Orthopedics, Warren Alpert Medical School of Brown University, Providence, Rhode Island, U.S.A.
Purpose: To determine the most effective number and location of fixation points for remplissage of Hill-Sachs lesions (HSL) in a cadaveric model of anterior shoulder instability.
Methods: Eleven fresh-frozen cadaveric shoulder specimens were tested. A robot device tested resistance to anterior translation of the humeral head.
Sci Rep
February 2025
Chulabhorn Research Institute, Kamphaeng Phet 6 Road, Laksi, Bangkok, 10210, Thailand.
Obesity poses a significant global health challenge, necessitating the search for novel therapeutic agents to address this epidemic. Chromenes, known for their diverse bioactivities, hold promise as potential anti-obesity compounds, yet research in this area remains limited. This pioneering study represents the first exploration of synthetic chromenes as potential anti-obesity agents, unveiling the underlying molecular pathways governing adipogenesis and lipolysis.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!