Cerebral aspergillosis is an opportunistic fungal infection that is exceedingly rare in immunocompetent patients. The primary etiological locations for these infections typically involve the nasal cavity and hematological dissemination. A 62-year-old male, focused on wellness, presented with intermittent, nonprogressive headaches in the occipital region, generalized clonic-tonic seizures, and altered consciousness. A computed tomography scan revealed multiple small rim-enhancing lesions in both occipital lobes, with vasogenic edema in both occipital lobes adjacent to the confluence of the sinuses and the posterior superior sagittal sinus. In this case, superior sagittal sinus thrombosis secondary to cerebral aspergillosis was discovered, a condition not previously diagnosed in this specific location but manageable through surgical intervention. A combination of surgical resection and antifungal therapy resulted in favorable outcomes. The prognosis for patients depends significantly on early diagnosis and prompt, aggressive treatment.
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http://dx.doi.org/10.1055/s-0044-1791714 | DOI Listing |
Diagnostics (Basel)
March 2025
Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
This study used diffusion tensor imaging (DTI) to detect brain microstructural changes in participants with mild traumatic brain injury (mTBI) who experienced post-traumatic headaches, a common issue that affects quality of life and rehabilitation. Despite its prevalence, the mechanisms behind post-traumatic headache are not well understood. Participants were recruited from Level 1 trauma centers, and MRI scans, including T1-weighted anatomical imaging and DTI, were acquired 1 month post-injury.
View Article and Find Full Text PDFGlobal Spine J
March 2025
Department of Neurosurgery, Rush University Medical Center, Chicago, IL, USA.
Study DesignSystematic Review.ObjectivesCervicothoracic junction (CTJ) deformities, particularly kyphosis, significantly impact patients' quality of life, causing pain, dysphagia, and inability to maintain horizontal gaze. Various surgical osteotomy techniques are available to correct CTJ kyphosis, but their relative effectiveness and associated complications remain unclear.
View Article and Find Full Text PDFEpilepsy Behav Rep
March 2025
Department of Stroke, Institute of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
Identifying epileptogenic zones non-invasively is challenging due to signal interference by the scalp and skull, necessitating invasive methods like subdural recordings and stereoelectroencephalography. Recent microcatheter advancements suggest that a microcatheter-compatible endovascular EEG (eEEG) device could overcome these barriers. We developed a thin, flexible eEEG electrode, the EP-01, for use with current microcatheters.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
December 2024
Department of Neurosurgery, Madurai Medical College, Madurai, Affiliated under The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, India.
Parasagittal and falcine meningiomas pose significant challenges to surgical removal due to their close proximity to the superior sagittal sinus and venous structures, posing high complications. The study evaluated the effectiveness of a microsurgical approach in reducing complication rates and achieving good tumor control in parasagittal and falcine meningiomas. A study involving 20 patients with parasagittal and falcine meningiomas underwent surgery at Madurai Medical College between January 2023 and December 2023.
View Article and Find Full Text PDFKurume Med J
March 2025
Department of General Medicine, All India Institute of Medical Sciences- Bibinagar, Hyderabad.
Background: Cerebral sinus venous thrombosis (CSVT) is a thrombosis of the cerebral veins and dural sinuses. It is a challenging condition for a physician due to varied symptoms. We aimed to study the clinical, radiological, etiology, and outcome of CSVT in a rural population.
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