Objective: The distribution characteristics of clinical isolates of were analyzed to provide the basis for the prevention and control of infection.
Methods: From January 2021 to December 2023, the First Affiliated Hospital of Nanjing Medical University collected clinical isolates of from hospitalized patients for study. Duplicate strains from the same patient in the same area were eliminated, and community-, hospital-, and colonization infections were grouped.
Results: A total of 561 clinical isolates of were identified, with 402 (82.35%) originating from male patients and 159 (17.65%) from female patients. The percentage of individuals aged 51 to 90 years was 78.97% (443/561). With the exception of surgery, which predominantly involved colonization, other departments mainly exhibited community-acquired infections (CAI) (=0.002). The length of hospital stay was less than <15-30 days for most cases in the healthcare-associated infection group (HAI) (<0.001). Lower respiratory tract infection accounted for the main site of infection across all three groups (95.37%), with ventilator-associated pneumonia being most prevalent in the HAI group (<0.001). The detection rates of from 2021 to 2023 were 3.89‱, 7.15‱, and 12.50‱, respectively. The detection frequencies of throughout the three groups exhibited a year-on-year increase (P<0.001). Sputum samples constituted the main source of clinical isolates for all three groups, accounting for 61 strains (89.71%), 277 strains (78.69%), and 122 strains (86.52%) respectively, followed by bronchoalveolar lavage fluid samples.
Conclusion: The detection rate of has exhibited a consistent upward trend over the past three years, with varying epidemiological characteristics observed across different infection types. It is recommended that medical institutions develop targeted prevention and control measures for infections based on these unique characteristics.
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| http://dx.doi.org/10.2147/IDR.S507944 | DOI Listing |
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