Paraovarian cysts develop near the ovaries and fallopian tubes in the pelvic region. We describe our experience with a case of endometrioid carcinoma arising from a paraovarian cyst to help others better understand its presentation and management. The patient was a 49-year-old woman (gravida 4, para 3) who presented with complaints of right hypochondrium pain. She underwent laparotomy based on a preoperative diagnosis of malignant ovarian tumor. As the intraoperative pathological diagnosis of the tumor was a borderline malignant tumor, a total abdominal hysterectomy, bilateral salpingo-oophorectomy was performed. Histologic findings were endometrioid carcinoma arising from the paraovarian cyst. After discussion with the patient and her family, we decided to forego adjuvant therapy and lymph node dissection and to continue with outpatient clinical follow-up only.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879078 | PMC |
| http://dx.doi.org/10.1093/jscr/rjaf002 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Preoperative predictors of concurrent endometrial carcinoma in patients with endometrial intraepithelial neoplasia: the role of HALP score and other inflammatory markers.
J Turk Ger Gynecol Assoc
March 2025
Department of Gynecologic Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.
Objective: The aim of this study was to identify preoperative factors that predict concurrent endometrial carcinoma in patients with endometrial intraepithelial neoplasia (EIN), focusing on inflammatory markers, such as hemoglobin, albumin, lymphocyte, and platelet (HALP) score, prognostic nutritional index (PNI), the modified systemic inflammatory score (mSIS), clinical characteristics, and imaging findings.
Material And Methods: A retrospective review was conducted of patients diagnosed with EIN who underwent hysterectomy and bilateral salpingo-oophorectomy between 2019 and 2024. Data collected included demographic details, cancer antigen-125 levels, hematological parameters, HALP score, PNI, mSIS, and preoperative endometrial thickness.
Establishment of a Novel In Vitro and In Vivo Model to Understand Molecular Carcinogenesis of Endometriosis-Related Ovarian Neoplasms.
Int J Mol Sci
February 2025
Department of Obstetrics and Gynecology, Faculty of Medicine, Shimane University, Izumo 693-8501, Japan.
The molecular mechanisms through which endometriosis-related ovarian neoplasms (ERONs) develop from benign endometrioma remain unclear. It is especially a long-standing mystery why ovarian endometrioma has the potential to develop into two representative histological subtypes: endometrioid ovarian carcinoma or clear cell ovarian carcinoma. This study aimed to investigate the molecular carcinogenesis of ERONs using newly developed in vitro and in vivo carcinogenesis models.
View Article and Find Full Text PDFKIF11 and KIF14 Are a Novel Potential Prognostic Biomarker in Patients with Endometrioid Carcinoma.
Cancers (Basel)
February 2025
Department of Clinical Pathomorphology, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, 85-094 Bydgoszcz, Poland.
The current study aimed to evaluate the function of KIF11 and KIF14 in endometroid cancer and assess their role as a prognostic biomarker and therapeutic target for treating endometroid cancer. Therefore, we immunohistochemically tested KIF11 and KIF14 proteins in tumoral and non-tumoral tissue sections from = 92 endometroid cancer patients with respect to major prognostic and predictive characteristics, as well as treatment outcome. We found that KIF11 protein levels were higher in tumor tissues as compared to normal tissues, whereas KIF14 protein levels were lower in cancer tissue.
View Article and Find Full Text PDFEndometriosis and cancer risk.
Eur J Cancer Prev
March 2025
Department of Oncology and Hemato-Oncology, University of Milan.
Endometriosis is one of the most common gynecological benign disease. Epidemiological evidence suggests a potential association between endometriosis and cancer risk. Accumulating evidence highlighted the risk of ovarian cancer, particularly endometrioid and clear cell subtypes.
View Article and Find Full Text PDFIntroduction of AGPAT3 gene as a regulator of cisplatin resistance in A2780 ovarian endometrioid carcinoma cell line.
PLoS One
March 2025
Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Ovarian cancer therapy remains a challenge for human health, partly due to chemotherapy resistance. Understanding the molecular mechanisms underlying this resistance is crucial. Therefore, to identify genes involved in cisplatin resistance in ovarian cancer, RNA-seq analysis of A2780cp (cisplatin-resistant) and A2780 (cisplatin-sensitive) cell lines was performed, revealing 1-acylglycerol-3-phosphate O-acyltransferase 3 (AGPAT3) as a differentially expressed candidate gene.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!