When measuring surface biopotentials there exists a trade-off between the spacing of the recording and reference electrodes, the fidelity of the recorded signals, and its susceptibility to motion artifacts and electromagnetic interference. In this paper, we propose and demonstrate the functionality of a wearable instrumentation patch that instead of measuring referenced biopotentials, measures local bioelectric field projections using a combination of passive differential referencing circuits, active shielding and a wide-dynamic-range instrumentation amplifier. As a result, the instrumentation patch can track biopotentials with magnitudes ranging from 1μV to 5mV, and even in the presence of significant motion artifacts. In this paper, we demonstrate different use cases and configurations of the patch for recording electrocardiogram (ECG) and electroencephalograph (EEG).
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http://dx.doi.org/10.1109/EMBC53108.2024.10782565 | DOI Listing |
Talanta
March 2025
Jiangxi Provincial Key Laboratory of Prevention and Treatment of Infectious Diseases, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, 330052, People's Republic of China. Electronic address:
The limitations of skin-interfaced sweat monitoring are mainly reflected in the effective collection of sweat and the high sensitivity of the detection. This work proposes a new type of sweat monitoring patch based on a flexible microfluidic chip fabricated by a capillary pump and a copper-based metal-based organic framework (Cu-MOF) sensitized electrochemical sensor. The sweat in the microchannel is driven by a capillary pump to ensure the smooth collection and transportation.
View Article and Find Full Text PDFSci Adv
March 2025
Affiliated Yueqing Hospital of Wenzhou Medical University, Wenzhou 325600, China.
Microneedles directly penetrating into the cornea inevitably cause pain, corneal structure damage, and reduced light transmittance. In this work, a minimally invasive annular microneedle (A-MN) patch was developed avoiding direct puncture into the central cornea for ophthalmic drug delivery. The feasible mechanical strength of A-MNs was achieved by adjusting the ratio of PVP-β-CD and PVA to puncture the cornea barrier.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Neurology, Pusan National University Hospital, Pusan National University School of Medicine, 179, Gudeok-ro, Seo-gu, Busan, 602-739, Korea.
We sought to compare the diagnostic efficacy of a 72-hour wearable electrocardiography (ECG) patch monitoring with a conventional 24-hour Holter monitoring for the detection of cardiogenic vertigo. We conducted a prospective multicenter study that recruited 47 patients suspected of cardiogenic vertigo in four referral-based university hospitals between November 2019 and April 2022. Patients received simultaneous ambulatory ECG recordings using a 72-hour wearable ECG patch monitoring and a conventional 24-hour Holter monitor.
View Article and Find Full Text PDFPersons who have experienced a prior myocardial infarction (MI) are at a greater risk of experiencing a secondary event. External factors, such as stress, can cause transient hypertension, further increasing cardiovascular disease risk. However, challenges to monitoring stress-induced hypertension include obtrusiveness of monitoring devices, unknown validity in high-risk populations, and unsubstantiated sensitivity in stressful environments.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
July 2024
Remote patient monitoring (RPM) enables healthcare professionals to virtually care for patients. This paper presents a novel RPM system, 'Leo' that includes a wearable chest patch, adhesives, charging cable, mobile application and a cloud-based analytics platform. It records ECG, impedance, accelerometer and gyroscope signals and outputs heart rate (HR), respiration rate (RR) and body position.
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