In this work, we propose a semi-autonomous device to measure the absorbance spectrum of a sample with high spectral resolution and high intensity precision to address the previously mentioned issues. The proposed system includes integrated optical, microfluidic and electronic modules. The optical module is based on a polychromator spectrophotometer using a Grism diffractive component for a high spectral resolution. The optical layout also includes a filter monochromator for high intensity precision. The electronic module controls all the subsystems while also communicating with a user interface for the data acquisition and analysis, and the microfluidic module allows to mix samples and handle the inlet and outlet vials. The spectral resolution of the completed system was tested with a mercury-argon lamp, and a spectral resolution of 0.38 nm was observed.
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http://dx.doi.org/10.1109/EMBC53108.2024.10782136 | DOI Listing |
Phys Med Biol
March 2025
Radiation Detection and Medical Imaging, Delft University of Technology Faculty of Applied Sciences, Mekelweg 15, 2629JB Delft, THE NETHERLANDS, Delft, 2628 CJ, NETHERLANDS.
Objective: Utilizing prompt gammas in preclinical pinhole-collimated PET avoids image degradation due to positron range blurring and photon down scatter, enables multi-isotope PET and can improve counting statistics for low-abundance positron emitters. This was earlier reported for 124I, 89Zr and simultaneous 124I -18F PET using the VECTor scanner (MILabs, The Netherlands), demonstrating sub-mm resolution despite long positron ranges. The aim of the present study is to investigate if such sub-mm PET imaging is also feasible for a large variety of other isotopes including those with extremely high energy prompt gammas (>1 MeV) or with complex emission spectra of prompt gammas.
View Article and Find Full Text PDFJ Biomed Opt
March 2025
University of Minnesota, Department of Biomedical Engineering, Minneapolis, Minnesota, United States.
Significance: We introduce a visible-light polarization-sensitive optical coherence tomography (PS-OCT) system that operates in the spectral domain with balanced detection (BD) capability. While the BD improves the signal-to-noise ratio (SNR), the use of shorter wavelengths improves spatial resolution and birefringence sensitivity.
Aim: We aim to implement a new optical design, characterize its performance, and investigate the imaging potential for biological tissues.
Cochlear Implants Int
March 2025
Department of Speech Language Pathology & Audiology, Towson University, Towson, MD, USA.
Objective: The objective of this study was to determine how the presentation of unprocessed speech, either ipsilaterally (to simulate electro-acoustic stimulation, EAS) or contralaterally (to simulate bimodal stimulation), alongside vocoder-processed speech affects the efficiency of spoken word processing.
Method: Gated word recognition was performed under four listening conditions: full-spectrum speech, vocoder-processed speech, electro-acoustic stimulation (EAS), and bimodal stimulation. In the EAS condition, low-frequency unprocessed speech and high-frequency vocoder-processed speech were presented to the same ear, while in the bimodal condition, full-spectrum speech was presented to one ear and vocoder-processed speech to the other.
ACS Nano
March 2025
School of Electrical and Electronics Engineering, Nanyang Technological University, 50 Nanyang Ave., Singapore 639798, Singapore.
Precise and dynamic observation of redox reactions in living organisms holds significant importance for the study of physiological processes and pathological mechanisms. However, the current technologies still make it challenging to monitor this process in a nondestructive and highly sensitive manner. Herein, we introduced a bioactive laser approach for ultrasensitive and real-time monitoring of intracellular redox reactions.
View Article and Find Full Text PDFJ Phys Chem B
March 2025
Department of Physics, Faculty of Science at Çanakkale Onsekiz Mart University, Çanakkale 17100, Turkey.
Over the last two decades, advancements in structural resolution and spectral characterization have significantly enhanced our understanding of photosynthesis. However, the complexity of photosystem (PS) supercomplexes still presents challenges. In the reaction center (RSRC), the charge separation process begins with a charge-transfer (CT) step at the special pair (P), a dimer of bacteriochlorophyll a (BChl), which acts as the donor, and continues with electron transport through the active pigments.
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