Rising diabetes rates have led to increased healthcare costs and health complications. An estimated half of diabetes cases remain undiagnosed. Early and accurate diagnosis is crucial to mitigate disease progression and associated risks. This study addresses the challenge of predicting diabetes prevalence in Canadian adults by employing machine learning (ML) techniques to primary care data. We leveraged the Canadian Primary Care Sentinel Surveillance Network (CPCSSN), Canada's premier multi-disease electronic medical record surveillance system, and developed and validated seven ML classification models to predict the likelihood of diabetes. The models were trained on clinical patient characteristics influential in predicting diabetes. We found XGBoost performed best out of all the models, with an AUC of 92%. The most important features contributing to model prediction were HbA1c level, LDL, and hypertension medication. Our research aims to aid healthcare professionals in early diagnosis and to identify key patient characteristics for targeted interventions. This study contributes to an understanding of how ML can enhance public health planning and reduce healthcare system burdens.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1109/EMBC53108.2024.10782432 | DOI Listing |
JAMA Netw Open
March 2025
Department of Epidemiology, University of North Carolina at Chapel Hill.
Importance: Numerous efforts have been made to include diverse populations in genetic studies, but American Indian populations are still severely underrepresented. Polygenic scores derived from genetic data have been proposed in clinical care, but how polygenic scores perform in American Indian individuals and whether they can predict disease risk in this population remains unknown.
Objective: To study the performance of polygenic scores for cardiometabolic risk factors of lipid traits and C-reactive protein in American Indian adults and to determine whether such scores are helpful in clinical prediction for cardiometabolic diseases.
Crit Rev Food Sci Nutr
March 2025
Department of Food Science and Nutrition, The Hong Kong Polytechnic University, Hong Kong SAR, China.
This study aims to review the evidence from Mendelian randomization (MR) studies on the causal role of vitamin D in type 2 diabetes (T2D). A systematic search (registered on PROSPERO (CRD42024551731)) was performed in PubMed, Embase and Web of Science for publications up to June 2024. MR studies including vitamin D as the exposure and T2D as the outcome were included.
View Article and Find Full Text PDFJ Diabetes Sci Technol
March 2025
Medicine and Pediatrics, Barbara Davis Center for Diabetes, Adult Clinic, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Automated insulin delivery (AID) systems adapt insulin delivery via a predictive algorithm integrated with continuous glucose monitoring and an insulin pump. Automated insulin delivery has become standard of care for glycemic management of people with type 1 diabetes (T1D) outside pregnancy, leading to improvements in time in range, with lower risk for hypoglycemia and improved treatment satisfaction. The use of AID facilitates optimal preconception care, thus more women of reproductive age are becoming pregnant while using AID.
View Article and Find Full Text PDFInt J Endocrinol Metab
October 2024
Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Metabolic Syndrome (MetS) is a prevalent condition associated with an increased risk of cardiovascular disease (CVD) and CVD mortality. Due to the limited clinical applicability of MetS, the standardized continuous metabolic syndrome severity score (cMetS-S) has the potential to provide continuous assessment of metabolic risk.
Objectives: This study evaluated the optimal cMetS-S cut-off points in the Tehran Lipid and Glucose Study (TLGS) for predicting CVD and CVD mortality.
Indian J Otolaryngol Head Neck Surg
February 2025
Department of Otorhinolaryngology and Head & Neck Surgery, King George Medical University, Lucknow, India.
Background: Presbyacusis is common in early 50s, while genetic/ environmental influences that differentially affect presbyacusis seem relevant in racial and regional perspective.
Aim: To describe audiometric profile of presbyacusis in North India and its relevance with age/ gender/ associated comorbidities.
Methods: Audiometric profile of about 7000 patients (> 50y) with SNHL were analysed in terms of curve-profile ('Flat', 'High-Frequency Gently Sloping', 'High-Frequency Steeply Sloping'), 'Mixed category', 'Interaural Asymmetry' and 'Notched Hearing Loss' along with their association with age, gender and co-morbidity status.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!