Epileptic seizures are clearly characterized by their displayed behavior, the semiology, which is used in diagnosis and classification as a base for therapy. This article presents a novel 4K 3D video recording and reviewing system for epilepsy monitoring, introducing a novel perspective and allowing continuous recording and review of 3D videos in the epilepsy monitoring unit (EMU), providing significantly more detail than the current clinical systems, which can lead to the recognition of more Movements of Interest (MOIs) and may reduce inter-rater variability. To put the system to an initial test in clinical practice the article presents three real-world examples of subtle MOIs, that could only be appreciated on the 4K-video, but not on the VGA-video, recorded as part of the clinical routine. In conclusion, a 4K-RGB recording, 3D cropping, and 3D video playing system was developed, implemented, and tested for realworld clinical scenarios, considering the specific requirements of clinical monitoring in EMUs. The new data acquisition setup can support clinical diagnosis, which may lead to new insights in the field of epilepsy and the development of AI approaches in the future.
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http://dx.doi.org/10.1109/EMBC53108.2024.10781546 | DOI Listing |
Ren Fail
December 2025
Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
Background: IgA nephropathy (IgAN) presents a challenging spectrum of outcomes, often complicated by intrarenal arterial/arteriolar lesions (IALs) in affected individuals. Despite their clinical relevance, existing criteria for classifying and assessing the severity of these lesions remain undefined. This study aimed to establish semi-quantitative assessment criteria for grading IALs and to evaluate their prognostic significance in patients with IgAN.
View Article and Find Full Text PDFEur J Neurosci
March 2025
School of Psychology, University of Auckland, Auckland, New Zealand.
The aim of the study was to determine the test-retest reliability of MMN and LDN recorded to simple speech contrasts in children with listening difficulties. MMN and LDN responses were recorded from Fz and Cz electrodes for a /da/-/ga/ contrast twice within a 10-day period. To extract MMN and LDN, auditory-evoked responses to /ga/ stimuli presented alone were subtracted from the responses to /ga/ presented within an oddball sequence.
View Article and Find Full Text PDFJ Cell Mol Med
March 2025
Hepatobiliary Center, the First Affiliated Hospital of Nanjing Medical University & Research Unit of Liver Transplantation and Transplant Immunology, Chinese Academy of Medical Sciences, Nanjing, Jiangsu, China.
The global incidence of biliary tract cancer (BTC) is on the rise, presenting a substantial healthcare challenge. The integration of immune checkpoint inhibitors (ICIs) with molecularly targeted therapies is emerging as a strategy to enhance immune responses. However, the efficacy and underlying mechanisms of these treatments in BTC are still largely unexplored.
View Article and Find Full Text PDFOrg Lett
March 2025
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Mohali 160062, India.
A one-pot process involving cycloaddition of the azaoxyallyl cation with thioamide and a synchronous E1-type elimination of the C2 amino group from the cycloadduct is disclosed, leading to diverse alkylidene-4-thiazolidinones. Amine elimination under acid-free conditions or without quaternization and forging a stereoselective olefin formation were among the interesting reactivity traits revealed through the present work. Conjugated thioamide permitted side-chain branching through a three-component process.
View Article and Find Full Text PDFLangmuir
March 2025
China Guangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology, School of Chemistry and Chemical Engineering, School of Resources, Environment and Materials, Guangxi University, Nanning 530004, China.
In the context of scarce metal resources, the one-step separation and recovery of high-value copper metal ions from secondary resources is of significant importance and presents substantial challenges. This study identified a Zn-based triazole MOF (Zn(tr)(OAc)) with accessible and noncoordinated terminal hydroxyl groups within its framework. The Zn(tr)(OAc) surpasses most currently reported Cu-specific MOF adsorbents regarding adsorption capacity and Cu selectivity.
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