Understanding the emotional dynamics within social interactions is crucial for meaningful interpretation. Despite progress in emotion recognition systems, recognizing the collective emotional climate among peers has been understudied. Addressing this gap, we propose EmoNet, an AI model transcending traditional emotion identification. EmoNet employs Mel-frequency cepstral coefficients and a Temporal Convolutional Network to extract deep features from speech signals. It uniquely integrates affect dynamics and physiological inputs (heart rate, electrodermal activity), providing a holistic view of emotion climates. Tested on K-EmoCon dataset, EmoNet excels in arousal and valence classification, achieving 87.82% and 83.79% accuracy, respectively. These results position EmoNet as a valuable tool for understanding and influencing emotion climates in real-world conversations, with applications in healthcare and human-computer interactions.
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http://dx.doi.org/10.1109/EMBC53108.2024.10782421 | DOI Listing |
J Chem Theory Comput
March 2025
School of Science, Constructor University, Campus Ring 1, 28759 Bremen, Germany.
The estimation of accurate free energies for antibiotic permeation via the bacterial outer-membrane porins has proven to be challenging. Atomistic simulations of the process suffer from sampling issues that are typical of systems with complex and slow dynamics, even with the application of advanced sampling methods. Ultimately, the objective is to obtain accurate potential of mean force (PMF) for a large set of antibiotics and to predict permeation rates.
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March 2025
Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, 214122, P.R. China.
Directed evolution, enzyme design, and effective immobilization have been used to improve the catalytic activity. Dynamic polymers offer a promising platform to improve enzyme activity in aqueous solutions. Here, amphiphilic dynamers and lipase self-assemble into nanoparticles of 150- to 600-nanometer diameter, showing remarkable threefold enhancement in catalytic activity.
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March 2025
The RNA Institute, University at Albany, State University of New York, Albany, NY 12222, USA.
DNA nanostructures are typically assembled by thermal annealing in buffers containing magnesium. We demonstrate the assembly of DNA nanostructures at constant temperatures ranging from 4° to 50°C in solutions containing different counterions. The choice of counterions and the assembly temperature influence the isothermal assembly of several DNA motifs and designed three-dimensional DNA crystals.
View Article and Find Full Text PDFQual Health Res
March 2025
Maternal and Fetal Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
This study investigated the use of group body mapping as a methodological tool to explore experiences of obstetric violence among migrant women from Senegal, Morocco, and Pakistan in Catalonia. The research aimed to assess the effectiveness of group body mapping in identifying the barriers these women faced during pregnancy, childbirth, and the postpartum period, while also highlighting the intersectional dimensions of obstetric violence. The study identified seven key codes-Issues/Barriers, Trust, Gender, Body/Embodiment, Significant Relationships, Employment, and Gender-Based Violence-which were analyzed from an intersectional perspective.
View Article and Find Full Text PDFPhys Chem Chem Phys
March 2025
School of Science, Shandong Jiaotong University, Jinan 250357, China.
The phosphorylation of residue T177 produces a significant effect on the conformational dynamics of CDK6. Gaussian accelerated molecular dynamics (GaMD) simulations followed by deep learning (DL) are applied to explore the molecular mechanism of the phosphorylation-mediated effect on the conformational dynamics of CDK6 bound by three inhibitors 6ZV, 6ZZ and 0RS, in which 6ZV and 6ZZ have been used to test clinical performance. The DL finds that the β-sheets, αC helix as well as the T-loop are involved in obvious differences of conformation contacts and suggests that the T-loop plays a key role in the function of CDK6.
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